Product Information
Name:
5-Hydroxy Vioxx
Synonyms:
- 5-Hydroxy-4-[4-(methylsulfonyl)phenyl]-3-phenyl-2(5H)-furanone
- 5-Hydroxyrofecoxib
- 2(3H)-furanone, dihydro-5-hydroxy-4-[4-(methylsulfonyl)phenyl]-3-phenyl-
Description:
Applications A metabolite of Vioxx. The biotransformation of Rofecoxib (Vioxx) was highly dependent on the subcellular fraction and the redox system used.
References Funaki, T., et al.: Biochem. Pharmacol., 38, 4213 (1989), John, B., et al.: Xenobiotica, 22, 1339 (1992), Jouzeau, J., et al.: Drugs, 53, 563 (1997), Baillie, T., et al.: Drug Metab. Dispos., 29, 1614 (2001),
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
330.36
Formula:
C17H14O5S
Color/Form:
Off-White to Light Yellow Solid
InChI:
InChI=1S/C17H14O5S/c1-23(20,21)13-9-7-12(8-10-13)15-14(16(18)22-17(15)19)11-5-3-2-4-6-11/h2-10,17,19H,1H3
InChI key:
InChIKey=NCBVUSNBLYMFPP-UHFFFAOYSA-N
SMILES:
CS(=O)(=O)c1ccc(C2=C(c3ccccc3)C(=O)OC2O)cc1
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