ICI 63197

CAS: 27277-00-5

Ref. TR-I163888

Product Information

• Name: ICI 63197
• Synonyms: 2-Amino-6-methyl-4-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-5(4H)-one, 2-Amino-4,5-dihydro-6-methyl-4-propyl-s-triazolo[1,5-a]pyrimidin-5-one, 2-Amino-6-methyl-4-propyl-4H-[1,2,4]triazolo[1,5-a]pyrimidin-5-one, 2-Amino-6-methyl-4-propyl-s-triazolo[1,5-a]pyrimid-5(4H)-one, 2-Amino-6-methyl-5-oxo-4-propyl-4,5-dihydro-s-triazolo[1,5-a]pyrimidine, (1,2,4)Triazolo(1,5-a)pyrimidin-5(4H)-one, 2-amino-6-methyl-4-propyl-, 2-Amino-4,5-dihydro-6-methyl-4-propyl-5-triazolo-(1,5-c)-pyramidin-5-one, 2-Amino-4,5-dihydro-6-methyl-4-propyl-s-triazolo-(1,5-A)-pyrimidin-5-one, 2-Amino-6-methyl-4-propyl-1,2,4-triazolo(1,5-a)pyrimidin-5(4H)-one, 2-Amino-6-methyl-4-propyl-4H,5H-[1,2,4]triazolo[1,5-a]pyrimidin-5-one, 2-Amino-6-methyl-4-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-5-one, 2-Amino-6-methyl-5-oxo-4n-propyl-4,5-dihydro-s-triazolo(1,5-a)pyrimidine, Caswell No. 033E, Ici 63197, Pp 769, Pp796, s-Triazolo[1,5-a]pyrimidin-5(4H)-one, 2-amino-6-methyl-4-propyl-
• CAS: 27277-00-5

Description

Applications ICI 63197 is a specific cAMP phosphodiesterase (PDE) inhibitor. It is potent in anatagonizing reserpine-induced hypothermia. potent PDE4 inhibitor.
References Schneider, H., et al.: Eur. J. Pharmacol., 127, 105 (1986); Wachtel, H.: Neuropharmacol., 22, 267 (1983);

• Brand: TRC

Chemical properties

• Molecular weight: 207.23
• Formula: C₉H₁₃N₅O
• Color/Form: Neat
• InChI: InChI=1S/C9H13N5O/c1-3-4-13-7(15)6(2)5-14-9(13)11-8(10)12-14/h5H,3-4H2,1-2H3,(H2,10,12)
• InChI key: InChIKey=UQDVRVNMIJAGRK-UHFFFAOYSA-N
• SMILES: CCCn1c(=O)c(C)cn2nc(N)nc12