Isoflupredone 21-Phosphate Ester Disodium Salt

CAS: 94088-00-3

Ref. TR-I816660

Product Information

• Name: Isoflupredone 21-Phosphate Ester Disodium Salt
• Synonyms: (11ß)-9-Fluoro-11,17-dihydroxy-21-(phosphonooxy)-pregna-1,4-diene-3,20-dione Disodium Salt, Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-21-(phosphonooxy)-, disodium salt, (11beta)-, Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-21-(phosphonooxy)-, sodium salt (1:2), (11β)-, disodium [2-[(8S,9R,10S,11S,13S,14S,17R)-9-fluoro-11,17-dihydroxy-10,13-dimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl] dihydrogen phosphate

Description

Stability Hygroscopic, Temperature Sensitive
Applications Isoflupredone 21-Phosphate Ester Disodium Salt is a derivative of Isofluopredone (I816600), an anti-inflammatory similar to Betamethasone (B327000).
References Ferrante, M.G., et al.: Anal. Profiles Drug Subs., 6, 43 (1977), Li, A., et al.: Chem. Biol. Interact., 142, 7 (2002), Cruz-Monteagudo, M., et al.: Eur. J. Med. Chem., 40, 1030 (2005), Rothfuss, A., et al.: Chem. Res. Toxicol., 19, 1313 (2006); Buchwald, P., et al.: Steroids, 73, 193 (2008), Holbeck, S., et al.: Mol. Endocrinol., 24, 1287 (2010),

• Brand: TRC

Chemical properties

• Molecular weight: 502.38
• Formula: C₂₁H₂₆FNa₂O₈P
• Color/Form: Neat
• InChI: InChI=1S/C21H28FO8P.2Na/c1-18-7-5-13(23)9-12(18)3-4-15-14-6-8-20(26,17(25)11-30-31(27,28)29)19(14,2)10-16(24)21(15,18)22;;/h5,7,9,14-16,24,26H,3-4,6,8,10-11H2,1-2H3,(H2,27,28,29);;/q;2*+1/p-2/t14-,15-,16-,18-,19-,20-,21-;;/m0../s1
• InChI key: InChIKey=RJCHGSGXNBHMRH-VJVYSMTMSA-L
• SMILES: C[C@]12C[C@H](O)[C@@]3(F)[C@@H](CCC4=CC(=O)C=C[C@@]43C)[C@@H]1CC[C@]2(O)C(=O)COP(=O)(O[Na])O[Na]