Isometronidazole-D4

CAS: 705-19-1

Ref. TR-I821342

Product Information

• Name: Isometronidazole-D4
• Synonyms: 2-Methyl-4-nitro-1H-imidazole-1-ethanol-D4, 1-(2-Hydroxyethyl)-2-methyl-4-nitroimidazole-D4, Izoklion-D4, Mizonidazole-D4, RP 8979-D4, SC-16427-D4, 1-(2-Hydroxyethyl)-2-methyl-4-nitro-1H-imidazole, 1-(2-Hydroxyethyl)-2-methyl-4-nitroimidazole, 2-(2-Methyl-4-nitro-imidazol-1-yl)-ethanol, 2-(2-Methyl-4-nitroimidazol-1-yl)ethanol, 2-Methyl-4-nitro-1H-imidazole-1-ethanol, Imidazole-1-ethanol, 2-methyl-4-nitro-, Imidazole-1-ethanol,2-methyl-4-nitro- (7CI,8CI), Isometronidazole, Izoklion, Mizonidazole, Rp 8979, Sc-16427
• CAS: 705-19-1

Description

Applications Isometronidazole-D4 is a labelled analogue of Isometronidazole (I821342). Isometronidazole is an impurity of Metronidazole (M338880), a chemotherapeutic agent that is used as a first line defense against Clostridium difficile (C.diff). Isometronidazole is also a hypoxic cell sensitizer in humans and mice.
References Hentschel, M. & Schmidt, W.: Die Pharm., 47, 221 (1992); Musher, D., et al.: Clin. Inf. Dis., 40, 1586 (2005); Rosenkranz, H. & Speck, W.: Biochem. Biophys. Res. Comm., 66, 520 (1975)

• Brand: TRC

Chemical properties

• Molecular weight: 175.18
• Formula: C₆H₅D₄N₃O₃
• Color/Form: Neat
• SMILES: [2H]C([2H])(O)C([2H])([2H])n1cc([N+](=O)[O-])nc1C