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(S)-Isopropyl-2-aminopropanoate-d7 Hydrochloride
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(S)-Isopropyl-2-aminopropanoate-d7 Hydrochloride

CAS: 343962-67-4

Ref. TR-I822222

25mg
1,065.00 €
Estimated delivery in United States, on Tuesday 7 Jan 2025

Product Information

Name:
(S)-Isopropyl-2-aminopropanoate-d7 Hydrochloride
Controlled Product
Synonyms:
  • L-Alanine 1-(Methyl-d3)ethyl-1,2,2,2-d4 Ester Hydrochloride (1:1)
Description:

Applications (S)-Isopropyl-2-aminopropanoate-d7 Hydrochloride is an intermediate in the synthesis of Desphenyl Tenofovir Alafenamide-d7 Ammonium Salt (D297044). Desphenyl Tenofovir Alafenamide-d7 Ammonium Salt is labeled form of Desphenyl Tenofovir Alafenamide (D297043), which belongs to a group of tenofovir diesters compounds, which can inhibit HIV-1 virus replication. Desphenyl Tenofovir Alafenamide can also be used to investigate the effect of oral absorption and lymphoid cell loading of GS-7340 (a prodrug of tenofovir). (S)-Isopropyl-2-aminopropanoate-d7 Hydrochloride is also the labelled form of (S)-Isopropyl-2-aminopropanoate Hydrochloride (I822220), which is a chemical reagent used in the synthesis of anti-HCV prodrugs based on imidazotriazine and pyrrolotriazine molecules.
References You, G., et al.: PCT Int. Appl. WO 2014026582 A1 2014022 (2014); Babusis, D., et al.: Mol. Pharm. 10, 459 (2013); Tyndall, E. Bioorg. Med. Chem. Lett., 25, 869 (2015)

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:

Chemical properties

Molecular weight:
174.68
Formula:
C6H6D7NO2·HCl
Color/Form:
Neat
InChI:
InChI=1S/C6H13NO2.ClH/c1-4(2)9-6(8)5(3)7;/h4-5H,7H2,1-3H3;1H/t5-;/m0./s1/i1D3,2D3,4D;
InChI key:
InChIKey=YAQKNCSWDMGPOY-SAADNGMHSA-N
SMILES:
Cl.[2H]C([2H])([2H])C([2H])(OC(=O)[C@H](C)N)C([2H])([2H])[2H]
MDL:
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EINECS:
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Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
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