Estimated delivery in United States, on Tuesday 18 Feb 2025
Product Information
Name:
JH-II-127
Controlled Product
Synonyms:
- [4-[[5-Chloro-4-(methylamino)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]amino]-3-methoxyphenyl]-4-morpholinyl-methanone
Description:
Applications JH-II-127 is a highly potent, selective, and brain penetrant LRRK2 inhibitor.
References Hatcher, J.M.; et al.: ACS Med. Chem. Lett., 6, 584 (2015)
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
416.87
Formula:
C19H21ClN6O3
Color/Form:
Neat
InChI:
InChI=1S/C19H21ClN6O3/c1-21-16-15-12(20)10-22-17(15)25-19(24-16)23-13-4-3-11(9-14(13)28-2)18(27)26-5-7-29-8-6-26/h3-4,9-10H,5-8H2,1-2H3,(H3,21,22,23,24,25)
InChI key:
InChIKey=HUEKBQXFNHWTQQ-UHFFFAOYSA-N
SMILES:
CNc1nc(Nc2ccc(C(=O)N3CCOCC3)cc2OC)nc2[nH]cc(Cl)c12
MDL:
Melting point:
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Flash point:
Density:
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EINECS:
Merck:
HS code:
Technical inquiry about: TR-J211303 JH-II-127
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