Estimated delivery in United States, on Friday 28 Jun 2024
Product Information
Name:
JT010
Synonyms:
- 2-Chloro-N-[4-(4-methoxyphenyl)-2-thiazolyl]-N-(3-methoxypropyl)acetamide
CAS:
Description:
Applications JT010 is a potent and selective TRPA1 channel activator (EC50 = 65 nM); activates the TRPA1 channel by covalently and site-selectively binding to Cys621. Exhibits selectivity for TRPA1 over TRPV1, TRPV3, TRPV4, TRPM2, TRPM8, and TRPC5 channels (EC50 values are >1 μM).
References Takaya, Junichiro., et al.: J. Am. Chem. Soc., 137, 15859 (2015);
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
354.85
Formula:
C16H19ClN2O3S
Color/Form:
Off-White to Light Beige Solid
InChI:
InChI=1S/C16H19ClN2O3S/c1-21-9-3-8-19(15(20)10-17)16-18-14(11-23-16)12-4-6-13(22-2)7-5-12/h4-7,11H,3,8-10H2,1-2H3
InChI key:
InChIKey=KZMAWJRXKGLWGS-UHFFFAOYSA-N
SMILES:
COCCCN(C(=O)CCl)c1nc(-c2ccc(OC)cc2)cs1
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:
Technical inquiry about: TR-J212028 JT010
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