23-Keto Nemadectin (Desmethoxyamino Moxidectin)

CAS: 112124-81-9

Ref. TR-K195535

Product Information

• Name: 23-Keto Nemadectin (Desmethoxyamino Moxidectin)
• Synonyms: (6R,25S)-5-O-Demethyl-28-deoxy-25-[(1E)-1,3-dimethyl-1-buten-1-yl]-6,28-epoxy-23-oxomilbemycin B, [6R,25S(E)]-5-O-Demethyl-28-deoxy-25-(1,3-dimethyl-1-butenyl)-6,28-epoxy-23-oxo-milbemycin B, Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2'-[2H]pyran] Milbemycin B derivative

Description

Applications 23-Keto Nemadectin (Desmethoxyamino Moxidectin) is a metabolite of Moxidectin (M744800), which is a parasiticide used for the prevention and control of heartworm and intestinal worms in veterinary medicine.
References Bisset, S.A. et al.: New Zeal. Vet. J., 40, 97 (1992); Monahan, C.M. et al.: Vet. Parasitol., 63, 225 (1996); Glickman, L.T. et al.: Int. J. Appl. Res. Vet. Med., 3, 49 (2005);

• Brand: TRC

Chemical properties

• Molecular weight: 610.78
• Formula: C₃₆H₅₀O₈
• Color/Form: Neat
• InChI: InChI=1S/C36H50O8/c1-20(2)13-24(6)32-25(7)30(37)18-35(44-32)17-28-16-27(43-35)12-11-22(4)14-21(3)9-8-10-26-19-41-33-31(38)23(5)15-29(34(39)42-28)36(26,33)40/h8-11,13,15,20-21,25,27-29,31-33,38,40H,12,14,16-19H2,1-7H3/b9-8+,22-11+,24-13+,26-10+/t21-,25-,27+,28-,29-,31+,32+,33+,35-,36+/m0/s1
• InChI key: InChIKey=VPWHZFYSDDOYRR-BVWZAJDSSA-N
• SMILES: CC1=C[C@H]2C(=O)O[C@H]3C[C@@H](C/C=C(\C)C[C@@H](C)/C=C/C=C4\CO[C@H]([C@@H]1O)[C@@]42O)O[C@@]1(CC(=O)[C@H](C)[C@@H](/C(C)=C/C(C)C)O1)C3