b-Lapachone (90%)

CAS: 4707-32-8

Ref. TR-L175300

Product Information

• Name: b-Lapachone (90%)
• Synonyms: 3,4-Dihydro-2,2-dimethyl-2H-naphtho[1,2-b]pyran-5,6-dione, ARQ 501, NSC 26326, NSC 629749, SL 11001, 2,2-Dimethyl-3,4-dihydrobenzo[h]chromene-5,6-dione, 2,2-dimethyl-3,4-dihydro-2H-benzo[h]chromene-5,6-dione, 2H-Naphtho(1,2-b)pyran-5,6-dione, 3,4-dihydro-2,2-dimethyl-, 3,4-Dihydro-2,2-dimethyl-2H-naphtho(1,2-b)pyran-5,6-dione, Arq-501, Brn 0181499, Lapachone, beta-, Mb 12066, Nsc 26326, Nsc 629749, Sl 11001, beta-Lapachone
• CAS: 4707-32-8

Description

Applications β-Lapachone is a naturally occurring quinone obtained from the bark of the lapacho tree (Tabebuia avellanedae) with cancer chemopreventive properties. Induces apoptosis in HL-60 and human prostate cancer cells.
References Renslo, A., et al.: Nat. Chem. Biol., 2, 701 (2006), Hopkins, A., et al.: Nat. Chem. Biol., 4, 682 (2008), Stuart, K., et al.: J. Clin. Invest., 118, 1301 (2008), Martin, R., et al.: Science, 25, 1680 (2009),

• Brand: TRC

Chemical properties

• Molecular weight: 242.27
• Formula: C₁₅H₁₄O₃
• Purity: 90%
• Color/Form: Orange Solid
• InChI: InChI=1S/C15H14O3/c1-15(2)8-7-11-13(17)12(16)9-5-3-4-6-10(9)14(11)18-15/h3-6H,7-8H2,1-2H3
• InChI key: InChIKey=QZPQTZZNNJUOLS-UHFFFAOYSA-N
• SMILES: CC1(C)CCC2=C(O1)c1ccccc1C(=O)C2=O