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Product Information
Name:
Linaclotide Ammonium Salt
Synonyms:
- Linzess Ammonium Salt
- 11: PN: WO2008151257 SEQID: 55 claimed protein Ammonium Salt 13: PN: WO2008151257 SEQID: 57 claimed protein Ammonium Salt
- 18: PN: WO2015054500 SEQID: 72 claimed protein Ammonium Salt
- 1: PN: WO2014131024 SEQID: 55 claimed protein Ammonium Salt,1: PN: WO2015054500 SEQID: 55 claimed protein Ammonium Salt,2074: PN: US20090062207 SEQID: 3 claimed protein Ammonium Salt
- 3: PN: WO2015054500 SEQID: 57 claimed protein Ammonium Salt
- 40: PN: WO2010065751 SEQID: 55 claimed protein Ammonium Salt
- 42: PN: WO2010065751 SEQID: 57 claimed protein Ammonium Salt,55: PN: US20100152118 SEQID: 55 claimed protein Ammonium Salt
- 55: PN: WO2011069038 SEQID: 55 claimed sequence Ammonium Salt
- 55: PN: WO2012037380 SEQID: 55 unclaimed protein Ammonium Salt
- 55: PN: WO2015054649 SEQID
- See more synonyms
CAS:
Description:
Stability Hygroscopic
Applications This compound is a salt form of Linaclotide (L465880). Linaclotide is a guanylate cyclase-C agonist currently being studied in Phase 3 trials for the treatment of irritable bowel syndrome with constipation.
References Chey, W.D., et al.: Am. J. Gastroenterol., 107, 1702 (2012); Rao, S., et al.: Am. J. Gastroentrol., 107, 1714 (2012); Brierley, S.M., et al.: Curr. Opinion. Pharmacol., 12, 632 (2012);
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
1526.74 + x(17.03)
Formula:
C59H79N15O21S6•x(NH
Color/Form:
White to Off-White Solid
InChI:
InChI=1S/C59H81N15O21S6.H3N/c1-28-48(83)71-42-26-101-100-25-41(72-49(84)34(60)22-97-99-23-39(64-27-75)52(87)69-37(20-44(61)79)58(93)74-16-3-4-43(74)56(91)65-28)54(89)67-35(13-14-46(81)82)51(86)68-36(18-30-5-9-32(77)10-6-30)50(85)62-15-17-96-98-24-40(66-45(80)21-63-57(92)47(29(2)76)73-55(42)90)53(88)70-38(59(94)95)19-31-7-11-33(78)12-8-31;/h5-12,27-29,34-43,47,76-78H,3-4,13-26,60H2,1-2H3,(H2,61,79)(H,62,85)(H,63,92)(H,64,75)(H,65,91)(H,66,80)(H,67,89)(H,68,86)(H,69,87)(H,70,88)(H,71,83)(H,72,84)(H,73,90)(H,81,82)(H,94,95);1H3/t28-,29+,34-,35+,36-,37-,38-,39-,40-,41-,42-,43-,47?;/m0./s1
MDL:
Melting point:
Boiling point:
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Density:
Concentration:
EINECS:
Merck:
HS code:
Technical inquiry about: TR-L465885 Linaclotide Ammonium Salt
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