Lorglumide

CAS: 97964-56-2

Ref. TR-L469913

Product Information

• Name: Lorglumide
• Synonyms: DL-4-(3,4-Dichlorobenzoylamino)-5-(dipentylamino)-5-oxopentanoic Acid, 4-[(3,4-Dichlorobenzoyl)amino]-5-(dipentylamino)-5-oxopentanoic Acid, CR 1409, (±)-4-[(3,4-Dichlorobenzoyl)amino]-5-(dipentylamino)-5-oxo-pentanoic Acid, 4-[(3,4-Dichlorobenzoyl)amino]-5-(dipentylamino)-5-oxo-pentanoic Acid, (+-)-4-(3,4-Dichlorobenzamido)-N,N-dipentylglutaramic acid, 4-[(3,4-Dichlorobenzoyl)amino]-5-(dipentylamino)-5-oxopentanoic acid, <span class="text-smallcaps">DL</span>-4-(3,4-Dichlorobenzoylamino)-5-(dipentylamino)-5-oxopentanoic acid, Ccris 6857, Cr 1409, D,L-4-(3,4-Dichlorobenzoylamino)-5-(dipentylamino)-5-oxo-pentanoic acid, Lorglumida, Lorglumida [Spanish], Lorglumide [INN], Lorglumidum, Lorglumidum [Latin], N~2~-(3,4-dichlorobenzoyl)-N,N-dipentyl-alpha-glutamine, Pentanoic acid, 4-((3,4-dichlorobenzoyl)amino)-5-(dipentylamino)-5-oxo-, (+-)-, Sodium 4-{[4-Carboxylato-1-(Dipentylamino)-1-Oxobutan-2-Yl]Carbamoyl}-1,2-Dichlorobenzene, Unii-Lad1Uq73Be

Description

Applications Lorglumide is a specific cholecytokinin receptor antagonist. It is also an intermediate in synthesizing Lorglumide Sodium Salt (L469910), a nonpeptidic antagonist of the CCK A receptor, and minimally effective at the CCK B receptor. It blocks CCK -mediated muscle contraction, pancreatic growth and secretion.
References Makovec, F. et al.: J. Med. Chem., 35, 28 (1992)

• Brand: TRC

Chemical properties

• Molecular weight: 459.41
• Formula: C₂₂H₃₂Cl₂N₂O₄
• Color/Form: White Solid
• InChI: InChI=1S/C22H32Cl2N2O4/c1-3-5-7-13-26(14-8-6-4-2)22(30)19(11-12-20(27)28)25-21(29)16-9-10-17(23)18(24)15-16/h9-10,15,19H,3-8,11-14H2,1-2H3,(H,25,29)(H,27,28)
• InChI key: InChIKey=IEKOTSCYBBDIJC-UHFFFAOYSA-N
• SMILES: CCCCCN(CCCCC)C(=O)C(CCC(=O)O)NC(=O)c1ccc(Cl)c(Cl)c1