Estimated delivery in United States, on Thursday 27 Jun 2024
Product Information
Name:
Mafodotin
Synonyms:
- L-Phenylalanine
- N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-N-methyl-L-valyl-L-valyl-(3R,4S,5S)-3-methoxy-5-methyl-4-(methylamino)heptanoyl-(aR,ßR,2S)-ß-methoxy-a-methyl-2-pyrrolidinepropanoyl-
- N-[6-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-N-methyl-L-valyl-L-valyl-(3R,4S,5S)-3-methoxy-5-methyl-4-(methylamino)heptanoyl-(aR,ßR,2S)-ß-methoxy-a-methyl-2-pyrrolidinepropanoyl-L-phenylalanine
- Maleimidocaproyl monomethylauristatin F
- Maleimidocaproyl-MMAF
- McMMAF
- SGD 1269
- mc-MMAF
- SGD-1269
- GSK3206291A
- See more synonyms
- GSK2857916
CAS:
Description:
Applications Mafodotin is an anticancer immunoconjugate for the diagnosis and treatment of cancer or B Cell proliferative diseases.
References Valliere-Douglass, J.F., et al.: Anal. Chem., 84, 2843 (2012); Alley, S.C., et al.: Bioconjugate. Chem., 19, 759 (2008); Doronina, S.O., et al.: Bioconjugate. Chem., 17, 114 (2006);
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
925.1613
Formula:
C49H76N6O11
Color/Form:
Neat
InChI:
InChI=1S/C49H76N6O11/c1-12-32(6)44(37(65-10)29-41(59)54-27-19-22-36(54)45(66-11)33(7)46(60)50-35(49(63)64)28-34-20-15-13-16-21-34)53(9)48(62)42(30(2)3)51-47(61)43(31(4)5)52(8)38(56)23-17-14-18-26-55-39(57)24-25-40(55)58/h13,15-16,20-21,24-25,30-33,35-37,42-45H,12,14,17-19,22-23,26-29H2,1-11H3,(H,50,60)(H,51,61)(H,63,64)/t32-,33+,35-,36-,37+,42-,43-,44-,45+/m0/s1
MDL:
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HS code:
Technical inquiry about: TR-M110280 Mafodotin
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