(5-Methoxycarbonylfuran-2-ylmethyl)triphenylphosphonium Chloride

CAS: 18812-25-4

Ref. TR-M188120

Product Information

• Name: (5-Methoxycarbonylfuran-2-ylmethyl)triphenylphosphonium Chloride
• CAS: 18812-25-4

Description

Applications (5-Methoxycarbonylfuran-2-ylmethyl)triphenylphosphonium Chloride is an intermediate in the synthesis of 5-[2-(5-Nitro-2-furanyl)ethenyl]-2-furancarboxylic Acid Methyl Ester (N493870), which is an inhibitor of G protein-coupled receptor kinase 2. 5-[2-(5-Nitro-2-furanyl)ethenyl]-2-furancarboxylic Acid Methyl Ester (N493870) was shown to normalize vascular endothelial function in type 2 diabetic mice by improving β-arrestin 2 translocation and ameliorating Akt/eNOS signal dysfunction.
References Taguchi, K., et al.: Endocrinol., 153, 2985 (2012);

• Brand: TRC

Chemical properties

• Molecular weight: 436.87
• Formula: C₂₅H₂₂ClO₃P
• Color/Form: White Solid
• InChI: InChI=1S/C25H22ClO3P/c1-28-25(27)24-18-17-20(29-24)19-30(26,21-11-5-2-6-12-21,22-13-7-3-8-14-22)23-15-9-4-10-16-23/h2-18H,19H2,1H3
• InChI key: InChIKey=KAAXAGDUYOHCQZ-UHFFFAOYSA-N
• SMILES: COC(=O)c1ccc(CP(Cl)(c2ccccc2)(c2ccccc2)c2ccccc2)o1