Estimated delivery in United States, on Tuesday 25 Jun 2024
Product Information
Name:
Maytansinol
Synonyms:
- Ansamitocin P 0
- Antibiotic C 15003P0
- NSC 239386
- 3-O-de[2-(Acetylmethylamino)-1-oxopropyl]maytansine
- Maytansine, O3-de2-(acetylmethylamino)-1-oxopropyl-
CAS:
Description:
Applications Maytansinol is used in the preparation of site-specific trastuzumab maytansinoid antibody-drug conjugates with improved therapeutic activity.
References Pillow, T.H., et. al.: J. Med. Chem., 57, 7890 (2014)
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
565.05
Formula:
C28H37ClN2O8
Color/Form:
Off-White to Orange Solid
InChI:
InChI=1S/C28H37ClN2O8/c1-15-8-7-9-22(37-6)28(35)14-20(38-26(34)30-28)16(2)25-27(3,39-25)21(32)13-23(33)31(4)18-11-17(10-15)12-19(36-5)24(18)29/h7-9,11-12,16,20-22,25,32,35H,10,13-14H2,1-6H3,(H,30,34)/b9-7+,15-8+/t16-,20+,21+,22-,25+,27+,28+/m1/s1
InChI key:
InChIKey=OKKDEIYWILRZIA-WMZQGNCFSA-N
SMILES:
Cl.Nc1ccn([C@@H]2O[C@H](CO)C(O)C2(F)F)c(=O)n1
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:
Technical inquiry about: TR-M197950 Maytansinol
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