Estimated delivery in United States, on Tuesday 11 Jun 2024
Product Information
Name:
Mergetpa
Synonyms:
- 3-[[2-[(Aminoiminomethyl)amino]ethyl]thio]-2-(mercaptomethyl)propanoic Acid
- (±)-2-(Mercaptomethyl)-3-(guanidinoethylthio)propionic Acid
- DL-2-(Mercaptomethyl)-3-(guanidinoethyl)thiopropanoic Acid
- Plummer's Carboxypeptidase Inhibitor
CAS:
Description:
Stability Air Sensitive, Hygroscopic
Applications Mergetpa is a potent mercapto bi-product analogue inhibitor for human carboxypeptidase N. Carboxypeptidase N is a potent bradykinin and anaphylatoxin inactivator in plasma. Mergetpa improves rt-PA induced thrombolysis in a dog model of coronary artery thrombosis.
References Barenholz, Y., et al.: Biochemistry, 16, 2806 (1977), Eaton, D., et al.: J. Biol. Chem., 266, 21833 (1991), Tan, A., et al.: Biochemistry, 34, 5811 (1995),
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
237.34
Formula:
C7H15N3O2S2
Color/Form:
Neat
InChI:
InChI=1S/C7H15N3O2S2/c8-7(9)10-1-2-14-4-5(3-13)6(11)12/h5,13H,1-4H2,(H,11,12)(H4,8,9,10)
InChI key:
InChIKey=AKPKWZRKZOAAAZ-UHFFFAOYSA-N
SMILES:
NC(N)=NCCSCC(CS)C(=O)O
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:
Technical inquiry about: TR-M225170 Mergetpa
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