Metergoline

CAS: 17692-51-2

Ref. TR-M226270

Product Information

• Name: Metergoline
• Synonyms: N-[[(8β)-1,6-Dimethylergolin-8-yl]methyl]-carbamic Acid Phenylmethyl Ester, Carbamic acid, [(1,6-dimethylergolin-8β-yl)methyl]-, benzyl ester (8CI), Carbamic acid, [[(8β)-1,6-dimethylergolin-8-yl]methyl]-, phenylmethyl ester (9CI), Lysergamine, N-carboxy-9,10-dihydro-1-methyl-, benzyl ester (7CI), Ergoline, carbamic acid deriv., Indolo[4,3-fg]quinoline, carbamic acid deriv., (+)-N-Carboxy-1-methyl-9,10-dihydrolysergamide benzyl ester, 8β-Carbobenzyloxyaminomethyl-1,6-dimethyl-10α-ergoline, AHR 3009, Contralac, D-8β-[(Carbobenzoxyamino)methyl]-1,6-dimethyl-10α-ergoline, D-8β-[(Carboxyamino)methyl]-1,6-dimethylergoline I benzyl ester, D-N-Carbobenzoxydihydro-1-methyllysergamine I, D-N-Carboxydihydro-1-methyllysergamine I benzyl ester, D-[(4,6,6a,7,8,9,10,10a-Octahydro-4,7-dimethyl-10aα-indolo[4,3-fg]quinolin-9β-yl)methyl]carbamic acid benzyl ester, FI 6337, Liserdol, MCE, Metergolin, Methergoline, [(1,6-Dimethylergolin-8β-yl)methyl]carbamic Acid Benzyl Ester
• Brand: TRC

Description

Applications Metergoline is an antagonist at 5-HT1, 5-HT2, and 5-HT7 serotonin receptors. Metergoline is an analgesic; antipyretic.
References Aulakh, et al.: J. Pharmacol. Exp. Ther., 263, 588 (1992), Miller, et al.: Eur. J. Pharmacol., 227, 99 (1992),

Chemical properties

• Molecular weight: 403.5167
• Formula: C₂₅H₂₉N₃O₂
• Color/Form: Neat
• InChI: InChI=1S/C25H29N3O2/c1-27-14-18(13-26-25(29)30-16-17-7-4-3-5-8-17)11-21-20-9-6-10-22-24(20)19(12-23(21)27)15-28(22)2/h3-10,15,18,21,23H,11-14,16H2,1-2H3,(H,26,29)/t18-,21+,23+/m0/s1
• InChI key: InChIKey=WZHJKEUHNJHDLS-QTGUNEKASA-N
• SMILES: CN1C[C@H](CNC(=O)OCc2ccccc2)C[C@@H]2c3cccc4c3c(cn4C)C[C@H]21