D-Methionine

CAS: 348-67-4

Ref. TR-M260550

Product Information

• Name: D-Methionine
• Synonyms: (R)-Methionine, MRX 1024, NSC 45689, S-Methyl-D-homocysteine, (2R)-2-Amino-4-methylsulfanylbutanoic acid, (R)-2-Amino-4-(Methylmercapto)Butyric Acid, (R)-2-Amino-4-(methylthio)butanoic acid, <span class="text-smallcaps">D</span>-Methionine, D-2-Amino-4-(Methylthio)Butyric Acid, D-Methionin, D-metionina, H-D-Met-OH, Methionine, <span class="text-smallcaps">D</span>-, Methionine, D-, Mrx 1024, Nsc 45689, S-Methyl-<span class="text-smallcaps">D</span>-homocysteine
• CAS: 348-67-4

Description

Applications D-Methionine is an isomer of L-Methionine (M260440) which is a cytoprotectant against Cisplatin (C499500), an anticancer agent. D-Methionine is also used to prevent noise- and drug-induced hearing loss, as well as hair loss (all of which may also be caused by Cisplatin or aminoglycosides).
References Campbell, K., et al.: Hear. Res., 92, 103 (2007); Cloven, N., et al.: Antican. Res., 20.6B, 4205 (1999); Vuyyuri, S., et al.: Clin. Cancer Res., 14, 2161 (2008)

• Brand: TRC

Chemical properties

• Molecular weight: 149.21
• Formula: C₅H₁₁NO₂S
• Color/Form: White to Pale Yellow Solid
• InChI: InChI=1S/C12H14O4/c1-8(6-12(13)14)10-5-4-9(15-2)7-11(10)16-3/h4-7H,1-3H3,(H,13,14)/b8-6+
• InChI key: InChIKey=VNLOISSPTMDCIF-SOFGYWHQSA-N
• SMILES: COc1ccc(/C(C)=C/C(=O)O)c(OC)c1