4-(Methoxycarbonyl)phenylboronic Acid

CAS: 1373752-82-9 99768-12-4

Ref. TR-M261675

Product Information

• Name: 4-(Methoxycarbonyl)phenylboronic Acid
• Synonyms: (4-Carbomethoxyphenyl)boronic Acid, 4-Carbomethoxybenzeneboronic Acid, 4-Methoxycarbonylbenzeneboronic Acid, Methyl 4-Boronobenzoate, Methyl p-Boronobenzoate, p-(Methoxycarbonyl)boronic Acid, p-(Methoxycarbonyl)phenylboronic Acid
• CAS: 1373752-82-9 99768-12-4

Description

Applications 4-(Methoxycarbonyl)phenylboronic Acid is used in the synthesis and evaluation of several organic compounds including that of 4-Cyclohexylbutyl-N-[(S)-2-oxoazetidin-3-yl]carbamate which is a potent inhibitor of intracellular NAAA activity. Also used in the design and synthesis of BMS-955176 which is a potent, orally active second generation HIV-1 maturation inhibitor.
References Nuzzi, A., et al.: Eur. J. Med. Chem., 111, 138 (2016); Rogueiro-Ren, A., et al.: ACS Med. Chem. Lett., 7, 568 (2016);

• Brand: TRC

Chemical properties

• Molecular weight: 179.97
• Formula: C₈H₉BO₄
• Color/Form: White Solid
• InChI: InChI=1S/C8H9BO4/c1-13-8(10)6-2-4-7(5-3-6)9(11)12/h2-5,11-12H,1H3
• InChI key: InChIKey=PQCXFUXRTRESBD-UHFFFAOYSA-N
• SMILES: COC(=O)c1ccc(B(O)O)cc1