2-Methoxy 17b-Estradiol

CAS: 362-07-2

Ref. TR-M262625

Product Information

• Name: 2-Methoxy 17b-Estradiol
• Synonyms: 2-Hydroxyestradiol 2-methyl ether, 2-Methoxy-E2, 2-Methoxyestradiol, 2ME2, NSC 659853, Panzem,Estradiol, 2-methoxy- (6CI), (17beta)-2-Methoxyestra-1,3,5(10)-triene-3,17-diol, Estra-1,3,5(10)-triene-3,17beta-diol, 2-methoxy- (7CI,8CI), 2-Methoxyestra-1,3,5(10)-triene-3,17beta-diol, (17Beta)-2-Methoxyestra-1(10),2,4-Triene-3,17-Diol, (17β)-2-Methoxyestra-1,3,5(10)-triene-3,17-diol, (9Xi,14Xi,17Beta)-2-Methoxyestra-1(10),2,4-Triene-3,17-Diol, 2-Hydroxyestradol 2-methyl ether, 2-Methoxyestra-1(10),2,4-Triene-3,17-Diol, 2-Methoxyestra-1,3,5(10)-triene-3,17β-diol, 2-Methoxyestradiol-17beta, 2Me2, Estra-1,3,5(10)-triene-3,17-diol, 2-methoxy-, (17beta)-, Estra-1,3,5(10)-triene-3,17-diol, 2-methoxy-, (17β)-, Estra-1,3,5(10)-triene-3,17beta-diol, 2-methoxy-, Estra-1,3,5(10)-triene-3,17β-diol, 2-methoxy-, Estradiol, 2-methoxy-, Nsc 659853, Panzem, Unii-6I2Qw73Sr5
• CAS: 362-07-2

Description

Applications 2-Methoxy 17β-Estradiol is a natural metabolite of 17β-Estradiol which is devoid of estrogenic activity. Inhibits cell proliferation and angiogenesis. 2-Methoxy 17β-Estradiol binds to the colchicine binding site of tubulin, and has been suggested to function as a natural regulator of microtubule assembly and function.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Cushman, M., et al.: J. Med. Chem., 38, 2041 (1995), D’Amato, R.J., et al.: Proc. Natl. Acad. Sci. USA, 91, 3964 (1994), Forsis, T., et al.: Nature, 368, 237 (1994)

• Brand: TRC

Chemical properties

• Molecular weight: 302.41
• Formula: C₁₉H₂₆O₃
• Color/Form: Off White
• InChI: InChI=1S/C19H26O3/c1-19-8-7-12-13(15(19)5-6-18(19)21)4-3-11-9-16(20)17(22-2)10-14(11)12/h9-10,12-13,15,18,20-21H,3-8H2,1-2H3/t12-,13+,15-,18-,19-/m0/s1
• InChI key: InChIKey=CQOQDQWUFQDJMK-SSTWWWIQSA-N
• SMILES: COc1cc2c(cc1O)CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](O)CC[C@@H]12