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Product Information
Name:
(R)-3-Methylamino-1-(2-thienyl)-1-propanol
Synonyms:
- 2-Thiophenemethanol
- a-[2-(methylamino)ethyl]-
- (aR)-
- 2-Thiophenemethanol
- a-[2-(methylamino)ethyl]-
- (R)-
- (aR)-a-[2-(Methylamino)ethyl]-2-thiophenemethanol
- (1R)-3-(Methylamino)-1-(2-thienyl)-1-propanol
- (1R)-3-(Methylamino)-1-(thiophen-2-yl)propan-1-o
CAS:
Description:
Applications (R)-3-Methylamino-1-(2-thienyl)-1-propanol is a reactant used in the synthesis of enantiomerically pure Duloxetine (D721000), an antidepressant. A dual serotonin and norepinephrine reuptake inhibitor (SNRI). Used in treatment of stress urinary incontinence.
References Wong, D.T., et al.: Neuropsychopharmacology, 8, 23 (1993), Fuller, R.W., et al.: J. Pharmacol. Exp. Ther., 269, 132 (1994), Sharma, A., et al.: J. Clin. Pharmacol., 40, 161 (2000)
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
171.26
Formula:
C8H13NOS
Color/Form:
Neat
InChI:
InChI=1S/C8H13NOS/c1-9-5-4-7(10)8-3-2-6-11-8/h2-3,6-7,9-10H,4-5H2,1H3/t7-/m1/s1
InChI key:
InChIKey=DXBHDBLZPXQALN-LFHVAVFRSA-N
SMILES:
CO[C@@H]1O[C@H](CO)C2OC(C)(C)OC21
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:
Technical inquiry about: TR-M287170 (R)-3-Methylamino-1-(2-thienyl)-1-propanol
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