Methyl (3R)-3-(tert-Butyldimethylsilanyloxy)-5-oxo-6-(triphenylphosphanylidene)hexanoate

CAS: 147118-35-2

Ref. TR-M288100

Product Information

• Name: Methyl (3R)-3-(tert-Butyldimethylsilanyloxy)-5-oxo-6-(triphenylphosphanylidene)hexanoate
• Synonyms: Hexanoic acid, 3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-5-oxo-6-(triphenylphosphoranylidene)-, methyl ester, (R)-, (3R)-3-(tert-Butyldimethylsilanyloxy)-5-oxo-6-(triphenylphosphanylidene)hexanoic acid methyl ester, (R)-3-[(tert-Butyldimethylsilanyl)oxy]-5-oxo-6-(triphenylphosphanylidene)hexanoic acid methyl ester, R-(-)-Oxo-3-(tert-butyldimethylsilyloxy)-6-triphenylphosphoranediylhexanoic acid methyl ester, Hexanoic acid, 3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-5-oxo-6-(triphenylphosphoranylidene)-, methyl ester, (3R)-
• Brand: TRC
• Description: Stability HygroscopicApplications Methyl (3R)-3-(tert-Butyldimethylsilanyloxy)-5-oxo-6-(triphenylphosphanylidene)hexanoate was used to preapre pyrimidinyl- and pyrrolylheptenoates with HMG-CoA reductase inhibitory activities.References Watanabe, M., et al.: Bioorg. Med. Chem., 5, 437 (1997); Pfefferkorn, J., et al.: J. Med. Chem., 51, 31 (2008)

Chemical properties

• Molecular weight: 534.70
• Formula: C₃₁H₃₉O₄PSi
• Color/Form: Neat
• InChI: InChI=1S/C31H39O4PSi/c1-31(2,3)37(5,6)35-26(23-30(33)34-4)22-25(32)24-36(27-16-10-7-11-17-27,28-18-12-8-13-19-28)29-20-14-9-15-21-29/h7-21,24,26H,22-23H2,1-6H3/t26-/m1/s1
• InChI key: InChIKey=NGHMDNPXVRFFGS-IUYQGCFVSA-N
• SMILES: O=C[C@H](O)[C@H](O)COP(=O)(O)O