2,2’-Methylene Bis[Ranitidine]

CAS: 207592-21-0

Ref. TR-M304005

Product Information

• Name: 2,2’-Methylene Bis[Ranitidine]
• Synonyms: Ranitidine Hydrochloride Imp. I (EP), Ranitidine Imp. I (EP), 2,2'-Methylenebis[N-[2-[[[5-[(dimethyl-amino)methyl]furan-2-yl]methyl]sulphanyl]ethyl]-N'-methyl-2-nitroethene-1,1-diamine], AH 24065A, Ph Eur Ranitidine Impurity I, Ranitidine formaldehyde adduct (AH24065), formaldehyde adduct (AH 24065A), Ranitidine Hydrochloride Impurity I, Ranitidine Impurity I
• CAS: 207592-21-0

Description

Impurity Ranitidine EP Impurity I
Stability Light Sensitive, Temperature Sensitive
Applications 2,2’-Methylene Bis[Ranitidine] (Ranitidine EP Impurity I) is an impurity of histamine H2-receptor antagonist Ranitidine (R120000).
References Jones, M.D. et al.: J. Sep. Sci., 29, 2409 (2006); Kelly, M.A. et al.: J. Chrom. A, 798, 297 (1998);

• Brand: TRC

Chemical properties

• Molecular weight: 640.82
• Formula: C₂₇H₄₄N₈O₆S₂
• Color/Form: Pale Yellow to Dark Brown Sticky Solid to Solid
• InChI: InChI=1S/C27H44N8O6S2/c1-28-26(30-11-13-42-18-22-9-7-20(40-22)16-32(3)4)24(34(36)37)15-25(35(38)39)27(29-2)31-12-14-43-19-23-10-8-21(41-23)17-33(5)6/h7-10,28-31H,11-19H2,1-6H3/b26-24+,27-25+
• SMILES: CN/C(NCCSCc1ccc(CN(C)C)o1)=C(/C/C(=C(/NC)NCCSCc1ccc(CN(C)C)o1)[N+](=O)[O-])[N+](=O)[O-]