Methopterine

CAS: 2410-93-7

Ref. TR-M305370

Product Information

• Name: Methopterine
• Synonyms: Methotrexate Imp. C (EP), Methotrexate USP Related Compound C, Methotrexate USP RC C, N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic Acid, Glutamic acid, N-[p-[[(2-amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]methylamino]benzoyl]-, L- (7CI,8CI), Glutamic acid, N-[p-[[(2-amino-4-hydroxy-6-pteridinyl)methyl]methylamino]benzoyl]- (6CI), L-Glutamic acid, N-[4-[[(2-amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl]methylamino]benzoyl]- (9CI), 10-Methylfolic acid, 10-Methylpteroylglutamic acid, Methopterin, N10-Methylfolic acid, N10-Methylpteroylglutamic acid, NSC 107144, Methotrexate Related Compound C, Methotrexate Impurity C, <span class="text-smallcaps">L</span>-Glutamic acid, N-[4-[[(2-amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl]methylamino]benzoyl]-, <span class="text-smallcaps">L</span>-Glutamic acid, N-[4-[[(2-amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]methylamino]benzoyl]-, Glutamic acid, N-[p-[[(2-amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]methylamino]benzoyl]-, <span class="text-smallcaps">L</span>-, Glutamic acid, N-[p-[[(2-amino-4-hydroxy-6-pteridinyl)methyl]methylamino]benzoyl]-, N-(4-{[(2-amino-4-hydroxypteridin-6-yl)methyl](methyl)amino}benzoyl)glutamic acid, N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]methylamino]benzoyl]-<span class="text-smallcaps">L</span>-glutamic acid, N-[4-[[(2-Amino-4-hydroxy-6-pteridinyl)-methyl]methylamino]benzoyl]glutamic Acid, N¹⁰-Methylfolic acid, N¹⁰-Methylpteroylglutamic acid, glutamic acid, N-[4-[[(2-amino-4-hydroxy-6-pteridinyl)methyl]methylamino]benzoyl]-

Description

Impurity Methotrexate EP Impurity C; Methotrexate USP Related Compound C
Applications Methopterine (Methotrexate EP Impurity C) is a Folic acid (F680300) analogue. Methopterine is effective in the treatment of ectopic pregnancy. Methotrexate USP Related Compound C
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References McNamara, P., et al.: Drug Metab. Dispos., 20, 302 (1992), Soldin, O., et al.: Ther. Drug Monit., 24, 1 (2002), Nicoli, S., et al.: J. Pharm. Biomed. Anal., 41, 994 (2006),

• Brand: TRC

Chemical properties

• Molecular weight: 455.42
• Formula: C₂₀H₂₁N₇O₆
• Color/Form: Neat
• InChI: InChI=1S/C20H21N7O6/c1-27(9-11-8-22-16-15(23-11)18(31)26-20(21)25-16)12-4-2-10(3-5-12)17(30)24-13(19(32)33)6-7-14(28)29/h2-5,8,13H,6-7,9H2,1H3,(H,24,30)(H,28,29)(H,32,33)(H3,21,22,25,26,31)/t13-/m0/s1
• InChI key: InChIKey=NEMMESQJOZVCAX-WHXUTIOJSA-N
• SMILES: CC(=O)OC1COC[C@H](OC(C)=O)C1OC(C)=O