(R)-N-Methyl-Laudanosine Iodide

CAS: 41431-32-7

Ref. TR-M315665

Product Information

• Name: (R)-N-Methyl-Laudanosine Iodide
• Synonyms: (R)-6,7-dimethoxy-2,2-dimethyliodide, (-)-Laudanosine Methiodide, (R)-N-Methyllaudanosinium Iodide, D-(-)-Laudanosine Methiodide
• CAS: 41431-32-7

Description

Applications (R)-N-Methyl-Laudanosine Iodide is a derivative of Laudanosine (L178525) a metabolite of the neuromuscular-blocking drugs Atracurium (A794500) and Cisatracurium (C496700) with potentially toxic systemic effects. It crosses the blood-brain barrier and may cause excitement and seizure activity.
References Canfell, P., et al.: Drug Metab. Dispos., 14, 703 (1986), Anselmi, E., et al.: J. Pharm. Pharmacol., 44, 337 (1992), Bohrer, H., et al.: Pharmacol. Toxicol., 73, 137 (1993),

• Brand: TRC

Chemical properties

• Molecular weight: 499.38
• Formula: C₂₂H₃₀INO₄
• Color/Form: White to Off-White Solid
• SMILES: COc1ccc(C[C@@H]2c3cc(OC)c(OC)cc3CC[N+]2(C)C)cc1OC.[I-]