6α-Methyl Prednisolone Aceponate

CAS: 86401-95-8

Ref. TR-M325725

Product Information

• Name: 6α-Methyl Prednisolone Aceponate
• Synonyms: Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-11-hydroxy-6-methyl-17-(1-oxopropoxy)-, (6a,11ß)-, (6a,11ß)-21-(Acetyloxy)-11-hydroxy-6-methyl-17-(1-oxopropoxy)pregna-1,4-diene-3,20-dione, Advantan, Methylprednisolone aceponate, ZK 91588, 6a-Methylprednisolone aceponate, (6Alpha,11Beta)-21-(Acetyloxy)-11-Hydroxy-6-Methyl-3,20-Dioxopregna-1,4-Dien-17-Yl Propanoate, (6a,11b)-21-(Acetyloxy)-11-hydroxy-6-methyl-17-(1-oxopropoxy)pregna-1,4-diene-3,20-dione, (6a,11b)-21-(Acetyloxy)-11-hydroxy-6-methyl-3,20-dioxopregna-1,4-dien-17-yl propionate, (6alpha,11beta)-21-Acetoxy-11-hydroxy-6-methyl-3,20-dioxopregna-1,4-dien-17-yl propionate, 11b,17,21-Trihydroxy-6a-methylpregna-1,4-diene-3,20-dione 21-Acetate 17-Propionate, Comfoderm K, Pregna-1,4-Diene-3,20-Dione, 21-(Acetyloxy)-11-Hydroxy-6-Methyl-17-(1-Oxopropoxy)-, (6Alpha,11Beta)-, Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-11-hydroxy-6-methyl-17-(1-oxopropoxy)-, (6α,11β)-, Zk 91588

Description

Applications Used in treatment of seborrhoeic dermatitis includes topical treatments such as corticosteroids, antifungals, metronidazole and pimecrolimus.
References Miyachi, Y., et al.: Br. J. Dermatol., 114, 231 (1986), Rallis, E., et al.: Drugs Exp. Clin. Res., 30, 191 (2004), Ozcan, H., et al.: Eur. J. Dermatol., 17, 313 (2007),

• Brand: TRC

Chemical properties

• Molecular weight: 472.57
• Formula: C₂₇H₃₆O₇
• Color/Form: White To Off-White
• InChI: InChI=1S/C27H36O7/c1-6-23(32)34-27(22(31)14-33-16(3)28)10-8-19-18-11-15(2)20-12-17(29)7-9-25(20,4)24(18)21(30)13-26(19,27)5/h7,9,12,15,18-19,21,24,30H,6,8,10-11,13-14H2,1-5H3/t15-,18-,19-,21-,24+,25-,26-,27-/m0/s1
• InChI key: InChIKey=DALKLAYLIPSCQL-YPYQNWSCSA-N
• SMILES: CCC(=O)O[C@]1(C(=O)COC(C)=O)CC[C@H]2[C@@H]3C[C@H](C)C4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@@]21C