N10-Methyl Pteroic Acid

CAS: 5623-18-7

Ref. TR-M326265

Product Information

• Name: N10-Methyl Pteroic Acid
• Synonyms: 4-[[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]methylamino]benzoic acid, N(10)-methylpteroic acid, Benzoic acid, 4-[[(2-amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]methylamino]-, Benzoic acid, 4-[[(2-amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl]methylamino]- (9CI), Benzoic acid, p-[[(2-amino-4-hydroxy-6-pteridinyl)methyl]methylamino]- (8CI), Metfol-B, NSC 408937, Pteroic acid, N10-methyl-, Methotrexate Imp. D (EP), 4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]methylamino]benzoic acid, Benzoic Acid, 4-[[(2-Amino-1,4-Dihydro-4-Oxo-6-Pteridinyl)Methyl]Methylamino]-, Benzoic acid, 4-[[(2-amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]methylamino]-, Benzoic acid, p-[[(2-amino-4-hydroxy-6-pteridinyl)methyl]methylamino]-

Description

Impurity Methotrexate EP Impurity D
Applications N10-Methyl Pteroic Acid (Methotrexate EP Impurity D) is a Methotrexate (M260675) impurity D.
References Cramer, S., et al.: Cancer Res. 1984, 44, 1843 (1984), Hendel, J., et al.: Eur. J. Clin. Pharmacol., 26, 103 (1984),

• Brand: TRC

Chemical properties

• Molecular weight: 326.31
• Formula: C₁₅H₁₄N₆O₃
• Color/Form: Orange To Dark Red
• InChI: InChI=1S/C15H14N6O3/c1-21(10-4-2-8(3-5-10)14(23)24)7-9-6-17-12-11(18-9)13(22)20-15(16)19-12/h2-6H,7H2,1H3,(H,23,24)(H3,16,17,19,20,22)
• InChI key: InChIKey=QHNLFEQJGRZKTK-UHFFFAOYSA-N
• SMILES: CN(Cc1cnc2[nH]c(N)nc(=O)c2n1)c1ccc(C(=O)O)cc1