alpha-Methyl-DL-tryptophan

CAS: 153-91-3

Ref. TR-M327120

Product Information

• Name: alpha-Methyl-DL-tryptophan
• Synonyms: Tryptophan, a-methyl-, DL-Tryptophan, a-methyl-, Tryptophan, a-methyl-, DL- (8CI), a-Methyltryptophan, (±)-a-Methyltryptophan, 2-Amino-3-(1H-indol-3-yl)-2-methylpropanoic acid, 2-Azaniumyl-3-(1H-indol-3-yl)-2-methylpropanoate, DL-a-Methyltryptophan, NSC 9948, a-Methyl-DL-tryptophan, Alpha-Methyl-DL-Tryptophan, H-.alpha.-Me-DL-Trp-OH, A-Methyl-L-Tryptophan
• CAS: 153-91-3

Description

Applications α-methyl-DL-tryptophan is used as a blocker of ATBo, an amino acid transporter whose expression is upregulated in cancer. It is also a substrate or non-transported inhibitor of the amino acid transporter PAT2 (slc36a2).
References Karunakaran, J., et al.: J. Biochem., 414, 343 (2008); Edwards, N., et al.: Biochimica et Biophysica Acta, Biomembranes, 1808, 260 (2011)

• Brand: TRC

Chemical properties

• Molecular weight: 218.25
• Formula: C₁₂H₁₄N₂O₂
• Color/Form: Off White Solid
• InChI: InChI=1S/C12H14N2O2/c1-12(13,11(15)16)6-8-7-14-10-5-3-2-4-9(8)10/h2-5,7,14H,6,13H2,1H3,(H,15,16)
• InChI key: InChIKey=ZTTWHZHBPDYSQB-UHFFFAOYSA-N
• SMILES: CC(N)(Cc1c[nH]c2ccccc12)C(=O)O