mono-Methyl Terephthalate

CAS: 1679-64-7

Ref. TR-M328100

Product Information

• Name: mono-Methyl Terephthalate
• Synonyms: 1,4-Benzenedicarboxylic Acid Monomethyl Ester, Terephthalic Acid Monomethyl Ester, 4-(Carbomethoxy)benzoic Acid, 4-(Methoxycarbonyl)benzoic Acid, 4-[(Methyloxy)carbonyl]benzoic Acid, Hydrogen Methyl Terephthalate, Methyl 4-Carboxybenzoate, Methyl Hydrogen Terephthalate, Methyl p-Carboxybenzoate, Methyl p-Phthalate, Monomethyl terephthalate, NSC 210838, p-(Methoxycarbonyl)benzoic Acid, p-Carbomethoxybenzoic Acid, 1,4-Benzenedicarboxylic acid, 1-methyl ester, 1,4-Benzenedicarboxylic acid, monomethyl ester, 4-(Carbomethoxy)benzoic acid, 4-(Methoxycarbonyl)Benzoate, 4-(Methoxycarbonyl)benzoic acid, 4-[(Methyloxy)carbonyl]benzoic acid, Hydrogen methyl terephthalate, Methyl 4-carboxybenzoate, Methyl p-carboxybenzoate, Methyl p-phthalate, Monomethyl Terephthalate, mono-Methyl terephthalate, p-(Methoxycarbonyl)benzoic acid, p-Carbomethoxybenzoic acid
• CAS: 1679-64-7

Description

Applications: mono-Methyl Terephthalate is used in the synthesis of Hepatits C antiviral activity. Also used in the design and preparation of benzamide derivatives as BRAFV600E inhibitors, which if mutated, can influence malignancies and melanomas.
References Shi, J. et al.: ChemMedChem., 8, 722 (2013); Xie, Y. et al.: Bioorg. Med. Chem. Lett., 23, 1396

• Brand: TRC

Chemical properties

• Molecular weight: 180.16
• Formula: C₉H₈O₄
• Color/Form: White Solid
• InChI: InChI=1S/C9H8O4/c1-13-9(12)7-4-2-6(3-5-7)8(10)11/h2-5H,1H3,(H,10,11)
• InChI key: InChIKey=REIDAMBAPLIATC-UHFFFAOYSA-N
• SMILES: COC(=O)c1ccc(C(=O)O)cc1