Methylprednisolone 21-Propionate-d5

CAS: 138804-88-3

Ref. TR-M328232

Product Information

• Name: Methylprednisolone 21-Propionate-d5
• Synonyms: (6?,11?)-11,17-Dihydroxy-6-Methyl-21-(1-Oxopropoxy-D5)Pregna-1,4-Diene-3,20-Dione

Description

Applications Methylprednisolone 21-Propionate-d5 is the labeled analogue of Methylprednisolone 21-Propionate (M328230), a metabolite of 6α-Methyl Prednisolone Aceponate (M325725), which is used in treatment of seborrhoeic dermatitis includes topical treatments such as corticosteroids, antifungals, metronidazole and pimecrolimus.
References Miyamoto, Y., et. al.: Yakubutsu Dotai, 6, 605 (1991); Miyachi, Y., et al.: Br. J. Dermatol., 114, 231 (1986), Rallis, E., et al.: Drugs Exp. Clin. Res., 30, 191 (2004), Ozcan, H., et al.: Eur. J. Dermatol., 17, 313 (2007),

• Brand: TRC

Chemical properties

• Molecular weight: 435.565
• Formula: C₂₅D₅H₂₉O₆
• Color/Form: Neat
• InChI: InChI=1S/C25H34O6/c1-5-21(29)31-13-20(28)25(30)9-7-17-16-10-14(2)18-11-15(26)6-8-23(18,3)22(16)19(27)12-24(17,25)4/h6,8,11,14,16-17,19,22,27,30H,5,7,9-10,12-13H2,1-4H3/t14-,16-,17-,19-,22+,23-,24-,25-/m0/s1/i1D3,5D2
• InChI key: InChIKey=KNKJEUNXMFFFDU-UCYWFHHHSA-N
• SMILES: [2H]C([2H])([2H])C([2H])([2H])C(=O)OCC(=O)[C@@]1(O)CC[C@H]2[C@@H]3C[C@H](C)C4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@@]21C