4-Methyl-benzenesulfonic Acid 2-[3-(Dimethylphenylsilyl)cyclobutylidene]hydrazide

CAS: 847158-85-4

Ref. TR-M329155

Product Information

• Name: 4-Methyl-benzenesulfonic Acid 2-[3-(Dimethylphenylsilyl)cyclobutylidene]hydrazide
• Synonyms: N'-(3-(Dimethyl(phenyl)silyl)cyclobutylidene)-4-methylbenzenesulfonohydrazide
• CAS: 847158-85-4

Description

Applications 4-Methyl-benzenesulfonic Acid 2-[3-(Dimethylphenylsilyl)cyclobutylidene]hydrazide is an intermediate used in synthesizing 2-Cyclobutenyl-3-trifluoromethyl-5-chloro-1H-indole-1-carboxylic Acid Ethyl Ester, which is synthesized from 5-chloro-2-oxindole (C375030), that is used in the preparation of novel GSK-3β inhibitors as anticancer agents.
References Choi, M.J., et al.: Bull. Korean. Chem. Soc., 32, 2015 (2011); Otani, M., et al.: Bioorg. Med. Chem. Lett.. 20, 4259 (2010); Jhan, Y.H., et al.: Tetrahedron. Lett., 54, 1155 (2013); Hsieh, J.C., et al.: Org. Biomolec. Chem., 10, 6404 (2012);

• Brand: TRC

Chemical properties

• Molecular weight: 372.56
• Formula: C₁₉H₂₄N₂O₂SSi
• Color/Form: Neat
• InChI: InChI=1S/C19H24N2O2SSi/c1-15-9-11-17(12-10-15)24(22,23)21-20-16-13-19(14-16)25(2,3)18-7-5-4-6-8-18/h4-12,19,21H,13-14H2,1-3H3/b20-16-
• InChI key: InChIKey=TVGWKNPPKSMNLI-SILNSSARSA-N
• SMILES: Cc1ccc(S(=O)(=O)NN=C2CC([Si](C)(C)c3ccccc3)C2)cc1