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Product Information
Name:
Mibefradil Dihydrochloride Hydrate
Synonyms:
- Posicor Monohydrate
- Ro 40-5967 Monohydrate
- Methoxyacetic Acid (1S,2S)-2-[2-[[3-(1H-Benzimidazol-2-yl)propyl]methylamino]ethyl]-6-fluoro-1,2,3,4-tetrahydro-1-(1-methylethyl)-2-naphthalenyl Ester Dihydrochloride Monohydrate
- Methoxyacetic Acid (1S-cis)-2-[2-[[3-(1H-Benzimidazol-2-yl)propyl]methylamino]ethyl]-6-fluoro-1,2,3,4-tetrahydro-1-(1-methylethyl)-2-naphthalenyl Ester Dihydrochloride Monohydrate
- Ro 40-5967/001 Monohydrate
Description:
Applications Mibefradil Dihydrochloride is a nondihydropyridine calcium channel blocker with potent vasodilator but weak inotropic action. Mibefradil Dihydrochloride is used in the treatment of hypertension and chronic angina pectoris.
References Osterrieder, W. et al.: J. Cardio. Pharmacol., 13, 754 (1989); Veniant, M. et al.: J. Cardio. Pharmacol., 21, 544 (1993); Hefti, F. et al.: Arzneim.-Forsch., 40, 417 (1990);
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
495.64 + x(18.02) + (36.46)
Formula:
C29H38FN3O3•xHO•HCl
Color/Form:
White to Off-White Solid
InChI:
InChI=1S/C29H38FN3O3.H2O/c1-20(2)28-23-18-22(30)12-11-21(23)13-14-29(28,36-27(34)19-35-4)15-17-33(3)16-7-10-26-31-24-8-5-6-9-25(24)32-26;/h5-6,8-9,11-12,18,20,28H,7,10,13-17,19H2,1-4H3,(H,31,32);1H2/t28-,29-;/m0./s1
MDL:
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Merck:
HS code:
Technical inquiry about: TR-M341800 Mibefradil Dihydrochloride Hydrate
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