Mibefradil Dihydrochloride

CAS: 116666-63-8

Ref. TR-M341803

Product Information

• Name: Mibefradil Dihydrochloride
• Synonyms: (1S,2S)-2-(2-{[3-(1H-benzimidazol-2-yl)propyl](methyl)amino}ethyl)-6-fluoro-1-(propan-2-yl)-1,2,3,4-tetrahydronaphthalen-2-yl methoxyacetate dihydrochloride, (1S-Cis)-Orid, 2-(2-((3-(1H-Benzimidazol-2-Yl)Propyl)Methylamino)Ethyl)-Aceticaci, 6-Fluoro-1,2,3,4-Tetrahydro-1-(1-Methylethyl)-2-Naphthalenylester,Dihydrochl, Acetic acid, 2-methoxy-, (1S,2S)-2-[2-[[3-(1H-benzimidazol-2-yl)propyl]methylamino]ethyl]-6-fluoro-1,2,3,4-tetrahydro-1-(1-methylethyl)-2-naphthalenyl ester, hydrochloride (1:2), Acetic acid, methoxy-, (1S,2S)-2-[2-[[3-(1H-benzimidazol-2-yl)propyl]methylamino]ethyl]-6-fluoro-1,2,3,4-tetrahydro-1-(1-methylethyl)-2-naphthalenyl ester, dihydrochloride, Acetic acid, methoxy-, 2-[2-[[3-(1H-benzimidazol-2-yl)propyl]methylamino]ethyl]-6-fluoro-1,2,3,4-tetrahydro-1-(1-methylethyl)-2-naphthalenyl ester, dihydrochloride, (1S-cis)-, Mibefradil diHCl, Mibefradil dihydrochloride, Mibefradil hydrate dihydrochloride, Posicor, Ro 40-5967, Ro 40-5967 hydrate, (1S,2S)-2-[2[[3-(2-Benzimidazolylpropyl]methylamino]ethyl]-6-fluoro-1,2,3,4-tetrahydro-1-isopropyl-2-naphthyl methoxyacetate hydrate dihydrochloride, Ro 40-5967/001, Ro40-5967/001

Description

Applications Mibefradil dihydrochloride is selectively blocks Ca2+ entry into cells by inhibiting T-type Ca2+ channels.

• Brand: TRC

Chemical properties

• Molecular weight: 568.55
• Formula: C₂₉H₃₈FN₃O₃· 2HCl
• Purity: >90%
• Color/Form: Neat
• InChI: InChI=1S/C29H38FN3O3.ClH/c1-20(2)28-23-12-11-22(30)18-21(23)13-14-29(28,36-27(34)19-35-4)15-17-33(3)16-7-10-26-31-24-8-5-6-9-25(24)32-26;/h5-6,8-9,11-12,18,20,28H,7,10,13-17,19H2,1-4H3,(H,31,32);1H/t28-,29-;/m0./s1
• InChI key: InChIKey=UKGWRIXCWLUSJF-OCPPCWRMSA-N
• SMILES: COCC(=O)O[C@]1(CCN(C)CCCc2nc3ccccc3[nH]2)CCc2cc(F)ccc2[C@@H]1C(C)C.Cl