Midecamycin (>85%)

CAS: 35457-80-8

Ref. TR-M343250

Product Information

• Name: Midecamycin (>85%)
• Synonyms: Leucomycin V, 3,4B-dipropanoate, Oxacyclohexadecane, leucomycin V deriv., Aboren, Antibiotic SF 837, Antibiotic SF 837A1, Antibiotic YL 704B1, Espinomycin A, Macropen, Medecamycin A1, Medemycin, Medemycin A1, Midecamycin A1, Midecin, Momicine, Mydecamycin, Mydecamycin A1, Myoxam, NSC 154011, Normicina, Platenomycin B1, Rubimycin, SF 837, SF 837A1, Turimycin P3, YL 704B1, (4R,5S,6S,7R,9R,10R,11E,13E,16R)-6-{[(2S,3R,4R,5S,6R)-4-(Dimethylamino)-3-hydroxy-5-{[(2S,4R,5S,6S)-4-hydroxy-4,6-dimethyl-5-(propionyloxy)tetrahydro-2H-pyran-2-yl]oxy}-6-methyltetrahydro-2H-pyran-2-yl]oxy}-10-hydroxy-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)oxacyclohexadeca-11,13-dien-4-yl propanoate (non-preferred name), (4R,5S,6S,7R,9R,10R,11E,13E,16R)-6-{[(2S,3R,4R,5S,6R)-4-(dimethylamino)-3-hydroxy-5-{[(2S,4R,5S,6S)-4-hydroxy-4,6-dimethyl-5-(propanoyloxy)tetrahydro-2H-pyran-2-yl]oxy}-6-methyltetrahydro-2H-pyran-2-yl]oxy}-10-hydroxy-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)oxacyclohexadeca-11,13-dien-4-yl propanoate (non-preferred name), 252-578-0, Antibiotic SF 837A₁, Antibiotic YL 704B₁, De 4',4''-Dipropionate (Ester), Leucomycin V 3,4B-Dipropanoate, Leucomycin V, 3,4^B-dipropanoate, Macro-Dil, Medecamycin A₁, Medemycin A₁, Midecamycin, Midecamycin A₁, Mydecamycin A₁, Oxacyclohexadecane, leucomycin V deriv., Platenomycin B₁, SF 837A₁, Sf 837, Turimycin P₃, YL 704B₁
• CAS: 35457-80-8

Description

Applications A 16-membered ring macrolide antibiotic used in ophthalmology as well as other medical fields.
References Matsui, K. et al.: J. Inter. Cytokin Res., 24, 197 (2004); Schmalreck, A.F. et al.: Antiinfect Drugs Chemother., 14, 225 (1996); Tokuda, H. et al.: Chemother., 21, 887 (1973);

• Brand: TRC

Chemical properties

• Molecular weight: 813.97
• Formula: C₄₁H₆₇NO₁₅
• Purity: >85%
• Color/Form: Off-White
• InChI: InChI=1S/C41H67NO15/c1-11-30(45)54-29-21-32(47)51-24(4)16-14-13-15-17-28(44)23(3)20-27(18-19-43)37(38(29)50-10)57-40-35(48)34(42(8)9)36(25(5)53-40)56-33-22-41(7,49)39(26(6)52-33)55-31(46)12-2/h13-15,17,19,23-29,33-40,44,48-49H,11-12,16,18,20-22H2,1-10H3/b14-13+,17-15+/t23-,24-,25-,26+,27+,28+,29-,33+,34-,35-,36-,37+,38+,39+,40+,41-/m1/s1
• InChI key: InChIKey=DMUAPQTXSSNEDD-PKSLHKBKSA-N
• SMILES: CCC(=O)O[C@H]1[C@H](C)O[C@@H](O[C@@H]2[C@@H](C)O[C@@H](O[C@@H]3[C@@H](OC)[C@H](OC(=O)CC)CC(=O)O[C@H](C)CC=CC=C[C@H](O)[C@H](C)C[C@@H]3CC=O)[C@H](O)[C@H]2N(C)C)C[C@@]1(C)O