Mometasone-d5 (Major)

CAS: 105102-22-5

Ref. TR-M489997

Product Information

• Name: Mometasone-d5 (Major)
• Synonyms: (11ß,16a)-9,21-Dichloro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione-d5, (+)-Mometasone-d5, (11Beta,16Alpha)-9,21-Dichloro-11,17-Dihydroxy-16-Methylpregna-1,4-Diene-3,20-Dione, (11Beta,16Alpha)-9,21-Dichloro-11-Hydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-17-Yl Furan-2-Carboxylate, (11β,16α)-9,21-Dichloro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione, (8xi,11beta,16alpha)-9,21-Dichlor-11,17-dihydroxy-16-methylpregna-1,4-dien-3,20-dion, (8xi,11beta,16alpha)-9,21-Dichloro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione, (9R,10S,11S,13S,14S,16R,17R)-9-Chloro-17-(chloroacetyl)-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one, Pregna-1,4-Diene-3,20-Dione, 9,21-Dichloro-11,17-Dihydroxy-16-Methyl-, (8Xi,11Beta,16Alpha)-, Pregna-1,4-diene-3,20-dione, 9,21-dichloro-11,17-dihydroxy-16-methyl-, (11β,16α)-
• CAS: 105102-22-5

Description

Applications Mometasone-d5 is the Isotope labelled analogue of Mometasone (M489995), a potent topical corticosteroid. Mometasone has potent antiinflammatory activity and is used in the treatment of dermatological disorders.
References Schulz, M. et al.: Pharm. Zeit., 139, 28 (1994); Prakash, A. et al.: Drugs, 55, 145 (1998);

• Brand: TRC

Chemical properties

• Molecular weight: 432.39
• Formula: C₂₂H₂₃D₅Cl₂O₄
• Color/Form: Neat
• InChI: InChI=1S/C22H28Cl2O4/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,24)17(26)10-20(16,3)22(12,28)18(27)11-23/h6-7,9,12,15-17,26,28H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19+,20+,21+,22-/m1/s1/i4D2,9D,11D2
• InChI key: InChIKey=QLIIKPVHVRXHRI-QBMBNOGZSA-N
• SMILES: [2H]C1=C2C([2H])([2H])C[C@H]3[C@@H]4C[C@@H](C)[C@@](O)(C(=O)C([2H])([2H])Cl)[C@@]4(C)C[C@H](O)[C@]3(Cl)[C@@]2(C)C=CC1=O