![(AlphaR)-2-Fluoro-Alpha-methyl[1,1'-biphenyl]-4-acetate (AlphaS)-Alpha-Methylbenzenemethanamine](https://static.cymitquimica.com/products/TR/img/M763195.png "Click to enlarge")
(AlphaR)-2-Fluoro-Alpha-methyl[1,1'-biphenyl]-4-acetate (AlphaS)-Alpha-Methylbenzenemethanamine
CAS: 76319-53-4
Ref. TR-M763195
| 1g | Discontinued | ||
| 10g | Discontinued | ||
| 50g | Discontinued |
Product Information
Name:
(AlphaR)-2-Fluoro-Alpha-methyl[1,1'-biphenyl]-4-acetate (AlphaS)-Alpha-Methylbenzenemethanamine
Description:
Applications (αR)-2-Fluoro-α-methyl[1,1'-biphenyl]-4-acetate (αS)-α-Methylbenzenemethanamine is an intermediate in the synthesis of Rimacalib (R505015), an inhibitor of CaMKII, inhibits VEGF expression in human acute monocytic leukemia cell and SF macrophage obtained from patient with rheumatoid arthritis. This effect may contribute to the anti-arthritic effects of Rimacalib.
References Westra, Johanna., et al.: BMC Musculoskelet Disord.,11 , No pp. given. (2010);
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
244.26 + 121.18
Formula:
C15H13FO2•C8H11N
InChI:
InChI=1S/C15H13FO2.C8H11N/c1-10(15(17)18)12-7-8-13(14(16)9-12)11-5-3-2-4-6-11;1-7(9)8-5-3-2-4-6-8/h2-10H,1H3,(H,17,18);2-7H,9H2,1H3/t10-;7-/m10/s1
InChI key:
InChIKey=SXXYXEUZKYVLQA-JIJBYVMQSA-N
SMILES:
C[C@@H](C(=O)O)c1ccc(-c2ccccc2)c(F)c1.C[C@H](N)c1ccccc1
MDL:
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