![2-Methyl-4-((3aS,4S,6S)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)butan-…](https://static.cymitquimica.com/products/TR/img/M897550.png "Click to enlarge")
2-Methyl-4-((3aS,4S,6S)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)butan-2-ol
Ref. TR-M897550
| 100mg | Discontinued | ||
| 250mg | Discontinued | ||
| 500mg | Discontinued |
Product Information
Name:
2-Methyl-4-((3aS,4S,6S)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)butan-2-ol
Description:
Applications 2-Methyl-4-((3aS,4S,6S)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)butan-2-ol is an intermediate for the synthesis of 3-Hydroxy Bortezomib (H818150), which is a metabolite of Bortezomib (B675700); the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer.
References Nawrocki, S.T., et al.: Cancer Res., 65, 11510 (2005); Drahl, C.: Chem. and Eng. News, 87, 41 (2009)
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
266.18
Formula:
C15H27BO3
Color/Form:
Pale Yellow Oil
InChI:
InChI=1S/C15H27BO3/c1-13(2,17)6-7-16-18-12-9-10-8-11(14(10,3)4)15(12,5)19-16/h10-12,17H,6-9H2,1-5H3/t10-,11-,12?,15-/m0/s1
InChI key:
InChIKey=HXAXWOWJIJUJHK-JTHFCNIQSA-N
SMILES:
CC(C)(O)CCB1OC2C[C@@H]3C[C@@H](C3(C)C)[C@]2(C)O1
MDL:
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