Methyl 2-Benzyl-5-hydroxy-2H-pyrazole-3-carboxylate
CAS: 52867-49-9
Ref. TR-M948535
| 100mg | Discontinued | ||
| 250mg | Discontinued | ||
| 500mg | Discontinued |
Product Information
Name:
Methyl 2-Benzyl-5-hydroxy-2H-pyrazole-3-carboxylate
Synonyms:
- 1-Benzyl-3-hydroxy-5-methoxycarbonyl-1H-pyrazole,Methyl 2-benzyl-5-oxo-2,5-dihydro-1H-pyrazole-3-carboxylate
CAS:
Description:
Applications Methyl 2-benzyl-5-hydroxy-2H-pyrazole-3-carboxylate is an intermediate for the synthesis of CFM 1571 Hydrochloride (C291720), which acts as a soluble guanylyl cyclase (sGC) activator while ignoring adenylyl cyclase. Inhibits collagen-stimulated platelet aggregation in vitro.
References Kotzki, S. et al.: J. Pharm. Exp. Ther., 346, 424 (2013); Selwood, D>et al.: J. Med. CHem., 44, 78 (2001)
Notice:
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Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
232.24
Formula:
C12H12N2O3
Color/Form:
White Solid
InChI:
InChI=1S/C12H12N2O3/c1-17-12(16)10-7-11(15)13-14(10)8-9-5-3-2-4-6-9/h2-7H,8H2,1H3,(H,13,15)
InChI key:
InChIKey=UFYYVUADSYAISN-UHFFFAOYSA-N
SMILES:
COC(=O)c1cc(=O)[nH]n1Cc1ccccc1
MDL:
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