Nalmefene-d3

CAS: 55096-26-9

Ref. TR-N284402

Product Information

• Name: Nalmefene-d3
• Synonyms: (5a)-17-(Cyclopropylmethyl-d3)-4,5-epoxy-6-methylenemorphinan-3,14-diol, 6-Deoxo-6-methylenenaltrexone-d3, 6-Desoxy-6-methylenenaltrexone-d3, JF 1-d3, Nalmetrene-d3, ORF 11676-d3, (5Alpha)-17-(Cyclopropylmethyl)-6-Methylidene-4,5-Epoxymorphinan-3,14-Diol, (5alpha)-17-(Cyclopropylmethyl)-4,5-epoxy-6-methylenemorphinon-3,14-diol, (5α)-17-(Cyclopropylmethyl)-4,5-epoxy-6-methylenemorphinan-3,14-diol, 17-(Cyclopropylmethyl)-4,5alpha-epoxy-6-methylenemorphinan-3,14-diol, 6-Deoxo-6-methylenenaltrexone, 6-Desoxy-6-methylenenaltrexone, 9a-(Cyclopropylmethyl)-4,5alpha-epoxy-6-methylen-3,14-morphinandiol, Alcofene, Arthene, Cervene, Cessal, Fenarc, Hsdb 6761, Incystene, Jf 1, Jkb 121, Morphinan-3,14-diol, 17-(cyclopropylmethyl)-4,5-epoxy-6-methylene-, (5alpha)-, Morphinan-3,14-diol, 17-(cyclopropylmethyl)-4,5-epoxy-6-methylene-, (5α)-, Nalmefene [USAN:INN:BAN], Nalmefeno, Nalmefeno [INN-Spanish], Nalmefenum, Nalmefenum [INN-Latin], Nalmetrene, Nalmetreno, Nalmetreno [INN-Spanish], Nalmetrenum, Nalmetrenum [INN-Latin], Nocarex, Orf 11676, Soberal, Srd 174, Unii-Tov02Tdp9I
• CAS: 55096-26-9

Description

Applications A structural labelled analog of Naltrexone (N285780) with opiate antagonist activity used in pharmaceutical treatment of alcoholism. Other pharmacological applications of this compound aim to reduce food cravings, drug abuse and pulmonary disease in affected individuals. Used as an opioid-induced tranquilizer on large animals in the veterinary industry. Narcotic antagonist.
References Brittain, H.G., et al.: Anal. Profiles Drug Subs. Excip., 24, 351 (1996), Anton, R., et al.: J. Clin. Psychopharmacol., 24, 421 (2004), Bart, G., et al.: Neuropsychopharmacol., 30, 2254 (2005), Wu, X., et al.: Chem. Pharmacol. Bull., 54, 977 (2006),

• Brand: TRC

Chemical properties

• Molecular weight: 342.45
• Formula: C₂₁H₂₂D₃NO₃
• Color/Form: Neat
• InChI: InChI=1S/C21H25NO3/c1-12-6-7-21(24)16-10-14-4-5-15(23)18-17(14)20(21,19(12)25-18)8-9-22(16)11-13-2-3-13/h4-5,13,16,19,23-24H,1-3,6-11H2/t16-,19+,20+,21-/m1/s1/i11D2,13D
• InChI key: InChIKey=WJBLNOPPDWQMCH-TVFUAGGXSA-N
• SMILES: [2H]C1(C([2H])([2H])N2CC[C@]34c5c6ccc(O)c5O[C@H]3C(=C)CC[C@@]4(O)[C@H]2C6)CC1