6α-Naloxol-d5 Hydrochloride

CAS: 20410-95-1

Ref. TR-N284502

Product Information

• Name: 6α-Naloxol-d5 Hydrochloride
• Synonyms: (4R,4aS,7S,7aR,12bS)-3-(1,1,2,3,3-pentadeuterioprop-2-enyl)-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,7,9-triol;hydrochloride, (5alpha,6alpha)-4,5-Epoxy-17-(2-propenyl)morphinan-3,6,14-triol, (5α,6α)-4,5-Epoxy-17-(2-propen-1-yl)morphinan-3,6,14-triol, 6-Hydroxynaloxone, 6α-Naloxol, En 2265, Morphinan-3,6,14-triol, 4,5-epoxy-17-(2-propen-1-yl)-, (5α,6α)-, Morphinan-3,6,14-triol, 4,5-epoxy-17-(2-propenyl)-, (5α,6α)-, Morphinan-3,6α,14-triol, 17-allyl-4,5α-epoxy-, N-Allyl-14-hydroxy-7,8-dihydronormorphine, N-Allyl-7,8-dihydro-14-hydroxynormorphine, α-Naloxol

Description

Applications A labelled metabolite of Naloxone (N285000). Naltrexone analog and Naloxone analog neutral µ opioid antagonists and use thereof in treating drug abuse and pain.
References Chatterjie, N., et al.: J. Med. Chem., 18, 490 (1975), Bilsky, E., et al.: J. Pharmacol. Exp. Ther., 277, 484 (1996), Blokhina, E., et al.: Eur. J, Pharmacol., 406, 227 (2000),

• Brand: TRC

Chemical properties

• Molecular weight: 370.882
• Formula: C₁₉D₅H₁₈NO₄·HCl
• Color/Form: Neat
• InChI: InChI=1S/C19H23NO4.ClH/c1-2-8-20-9-7-18-15-11-3-4-12(21)16(15)24-17(18)13(22)5-6-19(18,23)14(20)10-11;/h2-4,13-14,17,21-23H,1,5-10H2;1H/t13-,14+,17-,18-,19+;/m0./s1/i1D2,2D,8D2
• InChI key: InChIKey=VFEZXRHXAKHILC-MJLGWRNOSA-N
• SMILES: Cl.[2H]C([2H])=C([2H])C([2H])([2H])N1CC[C@]23c4c5ccc(O)c4O[C@H]2[C@@H](O)CC[C@@]3(O)[C@H]1C5