Naloxone

CAS: 465-65-6

Ref. TR-N284995

Product Information

• Name: Naloxone
• Synonyms: Morphinan-6-one, 4,5-epoxy-3,14-dihydroxy-17-(2-propen-1-yl)-, (5a)-, Morphinan-6-one, 17-allyl-4,5a-epoxy-3,14-dihydroxy- (8CI), Morphinan-6-one, 4,5-epoxy-3,14-dihydroxy-17-(2-propenyl)-, (5a)- (9CI), Normorphinone, N-allyl-7,8-dihydro-14-hydroxy- (7CI), 12-Allyl-7,7a,8,9-tetrahydro-3,7a-dihydroxy-4aH-8,9c-iminoethanophenanthro[4,5-bcd]furan-5(6H)-one, NSC 70413, l-Naloxone, (-)-Naloxone, (5α)-4,5-Epoxy-3,14-dihydroxy-17-(2-propen-1-yl)morphinan-6-one, Morphinan-6-one, 17-allyl-4,5α-epoxy-3,14-dihydroxy-, Morphinan-6-one, 4,5-epoxy-3,14-dihydroxy-17-(2-propen-1-yl)-, (5α)-, Naloxon, Naloxona, Normorphinone, N-allyl-7,8-dihydro-14-hydroxy-, Nsc 70413, Morphinan-6-one, 4,5-epoxy-3,14-dihydroxy-17-(2-propenyl)-, (5α)-

Description

Applications Naloxone is a specific opioid antagonist. Narcotic antagonist.
References Jasinski, D.R., et al.: J. Pharmacol. Exp. Ther., 157, 420 (1967), McNicholas, L.F., et al.: Drugs, 27, 81 (1984), Hasson, M.M.A., et al.: Anal. Profiles Drug Subs., 14, 453 (1985), Stowe, C., et al.: Ann. Pharmacother., 27, 447 (1993),

• Brand: TRC

Chemical properties

• Molecular weight: 327.37
• Formula: C₁₉H₂₁NO₄
• Color/Form: Neat
• InChI: InChI=1S/C19H21NO4/c1-2-8-20-9-7-18-15-11-3-4-12(21)16(15)24-17(18)13(22)5-6-19(18,23)14(20)10-11/h2-4,14,17,21,23H,1,5-10H2/t14-,17+,18+,19-/m1/s1
• InChI key: InChIKey=UZHSEJADLWPNLE-GRGSLBFTSA-N
• SMILES: C=CCN1CC[C@]23c4c5ccc(O)c4O[C@H]2C(=O)CC[C@@]3(O)[C@H]1C5