Product Information
Name:
(-)-Alpha-Narcotinediol
Synonyms:
- 1,3-Dioxolo[4,5-g]isoquinoline
- 1,2-benzenedimethanol deriv.
- (-)-Narcotinediol
- NSC 132826
- NSC 279531
- Narcotinediol,[S-(R*,S*)]-3,4-Dimethoxy-α1-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)-1,2-benzenedimethanol
- α-Narcotinediol (8CI)
- (-)-α-Narcotinediol
- (S-(R*,S*))-3,4-Dimethoxy-alpha1-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-yl)-o-xylene-alpha,alpha'-diol
- (α<sup>1</sup>S)-3,4-Dimethoxy-α<sup>1</sup>-[(5R)-5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-1,2-benzenedimethanol
- See more synonyms
- 1,2-Benzenedimethanol, 3,4-dimethoxy-α<sup>1</sup>-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)-, [S-(R*,S*)]-
- 1,2-Benzenedimethanol, 3,4-dimethoxy-α<sup>1</sup>-[(5R)-5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-, (α<sup>1</sup>S)-
- 1,3-Dioxolo[4,5-g]isoquinoline, 1,2-benzenedimethanol deriv.
- [2-(Hydroxymethyl)-3,4-Dimethoxyphenyl](4-Methoxy-6-Methyl-5,6,7,8-Tetrahydro[1,3]Dioxolo[4,5-G]Isoquinolin-5-Yl)Methanol
- alpha-Narcotinediol
Description:
Applications (-)-α-Narcotinediol is a Narcotine derivative, a noscapinoid class of microtubule binding compounds that alter microtubule dynamics without affecting tubulin polymer mass. Noscapinoids show great promise as chemotherapeutic agents for the treatment of human cancers. Unlike Narcotine, (-)-α-Narcotinediol deos not inhibit small-intestinal transport in rats.
References Naik, P. et al.: J. Mol. Mod., 18, 307 (2012); Marazova, K. et al.: Pharmazie., 43, 561 (1988)
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
417.45
Formula:
C22H27NO7
Color/Form:
White Solid
InChI:
InChI=1S/C22H27NO7/c1-23-8-7-12-9-16-21(30-11-29-16)22(28-4)17(12)18(23)19(25)13-5-6-15(26-2)20(27-3)14(13)10-24/h5-6,9,18-19,24-25H,7-8,10-11H2,1-4H3/t18-,19+/m1/s1
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