Estimated delivery in United States, on Tuesday 28 May 2024
Product Information
Name:
Nitisinone-13C6
Controlled Product
Synonyms:
- 2-[2-Nitro-4-(trifluoromethyl)benzoyl]-1,3-cyclohexanedione-13C6
- NTBC-13C6
- Nitisone-13C6
- Orfadin-13C6
- SC 0735-13C6
CAS:
Description:
Applications Labelled Nitisinone. Nitisinone is a herbicidal triketone that inhibits 4-hydroxyphenylpyruvate dioxygenase (HPPD), an enzyme involved in plastoquinone biosynthesis in plants and in tyrosine catabolism in mammals. It is used in treatment of inherited tyrosinemia type I.
References Lindstedt, S., et al.: Lancet, 340, 813 (1992), Ellis, M.K., et al.: Toxicol. Appl. Pharmacol., 133, 12 (1995), Lock, E.A., et al.: J. Inherited Metab. Dis., 21, 498 (1998),
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
335.18
Formula:
C8C6H10F3NO5
Color/Form:
Light Beige To Brown
SMILES:
O=C(c1ccc(C(F)(F)F)cc1[N+](=O)[O-])[13CH]1[13C](=O)[13CH2][13CH2][13CH2][13C]1=O
MDL:
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EINECS:
Merck:
HS code:
Technical inquiry about: TR-N490137 Nitisinone-13C6
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