(+)-Norisoboldine Hydrochloride

CAS: 23599-69-1

Ref. TR-N692030

Product Information

• Name: (+)-Norisoboldine Hydrochloride
• Synonyms: 2,10-Dimethoxy-6aalpha-noraporphine-1,9-diol, Laurelliptine Hydrochloride, (6aS)-5,6,6a,7-Tetrahydro-2,10-dimethoxy-4H-dibenzo[de,g]quinoline-1,9-diol Hydrochloride, (+)-Laurelliptine Hydrochloride, (+)-N-Norisoboldine Hydrochloride, (S)-(+)-Laurelliptine Hydrochloride, (+)-Laurelliptine, (+)-N-Norisoboldine, (6aS)-1,10-dimethoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,9-diol, (6aS)-2,10-Dimethoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-1,9-diol, (6aS)-5,6,6a,7-Tetrahydro-2,10-dimethoxy-4H-dibenzo[de,g]quinoline-1,9-diol, (S)-(+)-Laurelliptine, 4H-Dibenzo[de,g]quinoline-1,9-diol, 5,6,6a,7-tetrahydro-2,10-dimethoxy-, (S)-, 4H-dibenzo[de,g]quinoline-1,9-diol, 5,6,6a,7-tetrahydro-2,10-dimethoxy-, (6aS)-, 6aα-Noraporphine-1,9-diol, 2,10-dimethoxy-

Description

Stability Hygroscopic
Applications (+)-Norisoboldine Hydrochloride is the acid form of (+)-Norisoboldine which is an anti-arthritis alkaloid isolated from radix linderae which has been shown to attenuate osteoclast differentiation and inflammatory bone erosion in aryl hydrocarbon receptor-dependant manner.
References Wei, Z. et al.: J. Biol. Sci., 11, 1113 (2015);

• Brand: TRC

Chemical properties

• Molecular weight: 349.809
• Formula: C₁₈H₁₉NO₄·HCl
• Color/Form: Neat
• InChI: InChI=1S/C18H19NO4.ClH/c1-22-14-8-11-10(6-13(14)20)5-12-16-9(3-4-19-12)7-15(23-2)18(21)17(11)16;/h6-8,12,19-21H,3-5H2,1-2H3;1H/t12-;/m0./s1
• InChI key: InChIKey=POXNVTUOIYRUGG-YDALLXLXSA-N
• SMILES: COc1cc2c(cc1O)C[C@@H]1NCCc3cc(OC)c(O)c-2c31.Cl