Product Information
Name:
NVP-BAG956
Synonyms:
- BAG 956
- NVP-BAG 956
- α,α-Dimethyl-4-[2-methyl-8-(3-pyridinylethynyl)-1H-imidazo[4,5-c]quinolin-1-yl]benzeneacetonitrile
- Bag 956
- 2-Methyl-2-[4-[2-methyl-8-[(pyridin-3-yl)ethynyl]imidazo[4,5-c]quinolin-1-yl]phenyl]propionitrile
- α,α,-Dimethyl-4-[2-methyl-8-[2-(3-pyridinyl)ethynyl]-1H-imidazo[4,5-c]quinolin-1-yl]-benzeneacetonitrile
- 2-Methyl-2-[4-(2-methyl-8-pyridin-3-ylethynyl-imidazo[4,5-C]quinolin-1-yl)-phenyl]-propionitrile
- 2-Methyl-2-{4-[2-methyl-8-(pyridin-3-ylethynyl)-1H-imidazo[4,5-c]quinolin-1-yl]phenyl}propanenitrile
- 2-Methyl-2-{4-[2-methyl-8-(3-pyridinylethynyl)-1H-imidazo[4,5-c]quinolin-1-yl]phenyl}propanenitrile
Description:
Applications NVP-BAG956 acts as a rapamycin inhibitor used in the treatment of various melanomas through cell-induced apoptosis. Also used in antileukemic therapies as a dual PI3K/PDK-1 inhibitor.
References Marone, R. et al.: Mol. Canc. Res., 7, 601 (2009); Weisberg, E. et al.: Blood, 111, 3723 (2008);
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
427.5
Formula:
C28H21N5
Color/Form:
White Solid
SMILES:
Cc1nc2ncc3ccc(C#Cc4cccnc4)cc3c2n1-c1ccc(C(C)(C)C#N)cc1
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