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Product Information
Name:
Oltipraz
Synonyms:
- 4-Methyl-5-pyrazinyl-3H-1,2-dithiole-3-thione
- NSC 347901
- RP 35972
- 3H-1,2-Dithiole-3-thione, 4-methyl-5-(2-pyrazinyl)-
- 3H-1,2-Dithiole-3-thione, 4-methyl-5-pyrazinyl-
- 4-Methyl-5-(2-pyrazinyl)-3H-1,2-dithiole-3-thione
- 4-methyl-5-(pyrazin-2-yl)-3H-1,2-dithiole-3-thione
- 5-(2-Pyrazinyl)-4-methyl-1,2-dithiole-3-thione
- Brn 0978110
- Ccris 4048
- See more synonyms
- Nsc 347901
- Oltipraz [INN]
- Oltiprazum
- Oltiprazum [INN-Latin]
- Rp 35972
- Unii-6N510Jul1Y
CAS:
Description:
Applications Oltipraz is a synthetic, substituted 1,2-dithiole-3-thione previously used in humans as an antischistosomal agent. Animal studies have demonstrated that oltipraz is a potent inducer of Phase II detoxification enzymes, most notably glutathione-S-transferase (GST). Oltipraz is now known to be used for tumor prevention purposes.
References Yu, Z., et al.: Diabetologia., 54, 922 (2011); Benson, A.B., et al.: J. Cell. Biochem. Suppl., 17, 278 (1993);
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
226.34
Formula:
C8H6N2S3
Color/Form:
Red Solid
InChI:
InChI=1S/C8H6N2S3/c1-5-7(12-13-8(5)11)6-4-9-2-3-10-6/h2-4H,1H3
InChI key:
InChIKey=CKNAQFVBEHDJQV-UHFFFAOYSA-N
SMILES:
Cc1c(-c2cnccn2)ssc1=S
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:
Technical inquiry about: TR-O586050 Oltipraz
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