Pomalidomide N-Carbonyl-3-nitrobenzoic Acid

CAS: 1001852-10-3

Ref. TR-P103185

Product Information

• Name: Pomalidomide N-Carbonyl-3-nitrobenzoic Acid
• Synonyms: Benzoic acid, 2-[[(2,6-dioxo-3-piperidinyl)amino]carbonyl]-3-nitro- (ACI), 2-[[(2,6-Dioxo-3-piperidinyl)amino]carbonyl]-3-nitrobenzoic acid (ACI)

Description

Applications Pomalidomide N-Carbonyl-3-nitrobenzoic Acid is an impurity of Pomalidomide, which is a thalidomide derivative, a potent inhibitor of TNF-α production. It is an antiinflammatory and antitumor agent used in the treatment of multiple myeloma.
References Ruchelman, A. et al.: Bioorg. Med. Chem. Lett., 23, 360 (2013); Latif, T. et al.: Exp. Hematol. Oncol., 1, 27 (2012); Man, H. et al.: Bioorg. Med. Chem. Lett., 13, 3415 (2003); Muller, G. et al.: Bioorg. Med. Chem. Lett., 9, 1625 (1999)

• Brand: TRC

Chemical properties

• Molecular weight: 321.242
• Formula: C₁₃H₁₁N₃O₇
• Color/Form: Neat
• InChI: InChI=1S/C13H11N3O7/c17-9-5-4-7(11(18)15-9)14-12(19)10-6(13(20)21)2-1-3-8(10)16(22)23/h1-3,7H,4-5H2,(H,14,19)(H,20,21)(H,15,17,18)
• InChI key: InChIKey=FEJBBSSDUGPALM-UHFFFAOYSA-N
• SMILES: O=C1CCC(NC(=O)c2c(C(=O)O)cccc2[N+](=O)[O-])C(=O)N1