(S,R)-Palonosetron Hydrochloride Contains up to ~35% (R,R)-isomer
CAS: 135729-76-9
Ref. TR-P165810
| 5mg | 299.00 € | ||
| 50mg | 2,011.00 € |
Estimated delivery in United States, on Wednesday 27 Nov 2024
Product Information
Name:
(S,R)-Palonosetron Hydrochloride Contains up to ~35% (R,R)-isomer
Controlled Product
Synonyms:
- 1H-Benz[de]isoquinolin-1-one
- 2-(3R)-1-azabicyclo[2.2.2]oct-3-yl-2,3,3a,4,5,6-hexahydro-
- hydrochloride (1:1)
- (3aS)-
- 1H-Benz[de]isoquinolin-1-one
- 2-(1-azabicyclo[2.2.2]oct-3-yl)-2,3,3a,4,5,6-hexahydro-
- monohydrochloride
- [R-(R*,S*)]- (9CI)
- (3aS)-2-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-2,3,3a,4,5,6-hexahydro-1H-benz[de]isoquinolin-1-one hydrochloride (1:1)
- RS 25233-197
- See more synonyms
Description:
Stability Hygroscopic
Applications The (S,R)-enantiomer of Palonosetron (P165800), a potent and selective antagonist, with 5-HT3 receptor in vitro. An impurity of Palonosetron.
References Clark, R.D., et al.: J. Med. Chem., 36, 2645 (1993), Wong, E.H.F., et al.: Br. J. Pharmacol., 114, 851 (1995), Grunberg, S.M., et al.: Expert. Opin. Pharmacother., 4, 2297 (2003), Eisenberg, P., et al.: Ann. Oncol., 15, 330 (2004), Siddiqui, M.A.A., et al.: Drugs, 64, 1125 (2004),
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
332.87
Formula:
C19H24N2O·ClH
Color/Form:
Neat
InChI:
InChI=1S/C19H24N2O.ClH/c22-19-16-6-2-4-14-3-1-5-15(18(14)16)11-21(19)17-12-20-9-7-13(17)8-10-20;/h2,4,6,13,15,17H,1,3,5,7-12H2;1H/t15-,17+;/m1./s1
InChI key:
InChIKey=OLDRWYVIKMSFFB-KALLACGZSA-N
SMILES:
Cl.O=C1c2cccc3c2[C@H](CCC3)CN1[C@H]1CN2CCC1CC2
MDL:
Melting point:
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Concentration:
EINECS:
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HS code:
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