Product Information
Name:
PD-184352
Synonyms:
- 2-[(2-Chloro-4-iodophenyl)amino]-N-(cyclopropylmethoxy)-3,4-difluorobenzamide
- 3,4-Difluoro-2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxybenzamide
- CI 1040
- Pd184352
- Ci1040
Description:
Applications An inhibitor of ERK signaling pathway. A MAP kinase inhibitor. Potent MEK inhibitor.
References Adeyinka, A., et al.: Clin. Cancer Res., 8, 1747 (2002), Saal, L., et al.: Cancer Res., 65, 2554 (2005), Berns, K., et al.: Cancer Cell, 12, 395 (2007),
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
478.66
Formula:
C17H14ClF2IN2O2
Color/Form:
Off-White to Pale Beige Solid
InChI:
InChI=1S/C17H14ClF2IN2O2/c18-12-7-10(21)3-6-14(12)22-16-11(4-5-13(19)15(16)20)17(24)23-25-8-9-1-2-9/h3-7,9,22H,1-2,8H2,(H,23,24)
InChI key:
InChIKey=GFMMXOIFOQCCGU-UHFFFAOYSA-N
SMILES:
O=C(NOCC1CC1)c1ccc(F)c(F)c1Nc1ccc(I)cc1Cl
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