Estimated delivery in United States, on Wednesday 26 Jun 2024
Product Information
Name:
PF-4708671
Synonyms:
- 2-[(4-(5-ethyl-4-pyrimidinyl)-1-piperazinyl)methyl]-6-(trifluoromethyl)-1H-benzimidazole
CAS:
Description:
Applications PF-4708671 is a highly specific inhibitor of p70 ribosomal S6 kinase (S6K1). PF-4708671 inhibits S6K1-mediated phosphorylation of S6 protein in response to IGF-1 (insulin-like growth factor 1), while having no effect on highly related RSK (p90 ribosomal S6 kinase) and MSK (mitogen- and stress-activated kinase) kinases.
References Pearce, L.R. et al.: Biochem. J., 431, 245 (2010);
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
390.40
Formula:
C19H21F3N6
Color/Form:
White to Off-White Solid
InChI:
InChI=1S/C19H21F3N6/c1-2-13-10-23-12-24-18(13)28-7-5-27(6-8-28)11-17-25-15-4-3-14(19(20,21)22)9-16(15)26-17/h3-4,9-10,12H,2,5-8,11H2,1H3,(H,25,26)
InChI key:
InChIKey=JRBZAPCQLIYXQP-UHFFFAOYSA-N
SMILES:
CC(N)c1ncccc1N
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:
Technical inquiry about: TR-P294010 PF-4708671
Please use instead the cart to request a quotation or an order
If you want to request a quotation or place an order, please instead add the desired products to your cart and then request a quotation or order from the cart. It is faster, cheaper, and you will be able to benefit from the available discounts and other advantages.
