Estimated delivery in United States, on Friday 28 Jun 2024
Product Information
Name:
PIK-75
Controlled Product
Synonyms:
- 2-Methyl-5-nitro-benzenesulfonic Acid [(6-Bromoimidazo[1,2-a]pyridin-3-yl)methylene]methylhydrazide
- Benzenesulfonicacid, 2-methyl-5-nitro-, [(6-bromoimidazo[1,2-a]pyridin-3-yl)methylene]methylhydrazide(9CI)
- Pik 75
- N'-[(1Z)-(6-bromoimidazo[1,2-a]pyridin-3-yl)methylidene]-N,2-dimethyl-5-nitrobenzenesulfonohydrazide
- Benzenesulfonic acid, 2-methyl-5-nitro-, [(6-bromoimidazo[1,2-a]pyridin-3-yl)methylene]methylhydrazide
CAS:
Description:
Applications PIK-75 is a p110α inhibitor, isoform-specific mutants at Ser773, and also potently inhibits DNA-PK.
References Zheng, Z., et al.: Mol. Pharmacol., 80, 657 (2011); Moir, L., et al.: J. Pharmacol. Exp. Ther., 337, 557 (2011); Jude, J., et al.: Am. J. Respir. Cell. Mol. Biol., 65, 2011
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
452.28
Formula:
C16H14BrN5O4S
Color/Form:
Light Yellow to Yellow Solid
InChI:
InChI=1S/C13H15N5O3S2/c1-17(2)23(19,20)11-4-3-10(12-13(11)16-21-15-12)18-6-5-9(7-18)14-8-22/h3-4,9H,5-7H2,1-2H3/t9-/m0/s1
InChI key:
InChIKey=YMXYIIXTKUQWPC-VIFPVBQESA-N
SMILES:
CN(C)S(=O)(=O)c1ccc(N2CC[C@H](N=C=S)C2)c2nonc12
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:
Technical inquiry about: TR-P437670 PIK-75
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